Generation of Reactive Oxygen Species during Apoptosis Induced by DNA-Damaging Agents and/or Histone Deacetylase Inhibitors

Figure 3

Western blots showing PARP fragmentation and caspase 3 activation during 24 h treatment of CML cells (a) or PBL (b). Cells were treated by actinomycin D (A), sodium butyrate (B), SAHA (S), decitabine (D), or their combination (AB, AS, DS). Symbol C denotes untreated cells. 𝛽-actin expression is showed as a loading control.