Chopper Is Prodeath Regardless of the Effect of p75ICD on Sensitivity to Oxidative Stress
Figure 3
(a) Light and fluorescent micrographs of stable HN33.11 cells expressing (A)-GFP or (B)-GFP, respectively. Results from two stable clones of each transfection pool are shown. Cells are treated with vehicle (Dox−) or 1 g/mL Dox (Dox+). (b) Western blot of homogenates of stable clones showing endogenous production of full-length p75NTR (FLp75), Dox-induced, but “leaky” production of (A) and (B) and of the V5 tag. Control values for each clone do not differ significantly between GFP(−) and GFP(+) cells (Student’s t-test). *** relative to GFP(−) cells.