Chopper Is Prodeath Regardless of the Effect of p75ICD on Sensitivity to Oxidative Stress
Figure 6
Hoechst dye staining of MCS, A37, and B2 cells 48 hours after treatment with 6-OHDA (150 μM, 1 hour exposure). Two-hundred total cells were counted in each treated well to determine the percent of the cells that exhibited nuclear condensation and/or fragmentation and margination of DNA. P values for A37 and B2 cells are calculated by Student’s t-test relative to MCS cells. Protection from morphologic apoptosis is greatest in B2 cells and less robust in A37 cells.
