Role of Oxidative Stress in Transformation Induced by Metal Mixture

Figure 8

Influence of N-acetyl-cysteine (NAC) on metal-mixture-induced transformation, lipid peroxidation. Cells were cotreated with 10 mM NAC and the metal mixture (2 𝜇M NaAsO₂, 2 𝜇M CdCl₂, and 5 𝜇M Pb(C₂H₃O₂)₂·3H₂O); samples were collected on day 16. Data represent the mean of three independent experiments performed in triplicate. LPx was measured as an oxidative stress marker. The results are presented as a percentage with respect to control values, as determined by the thiobarbituric acid method (ANOVA and Student’s t test **𝑃<0.001, ***𝑃<0.0001).