Lipid-Lowering and Antioxidative Activities of Aqueous Extracts of Ocimum sanctum L. Leaves in Rats Fed with a High-Cholesterol Diet
Figure 4
Histopathological appearance of thoracic aorta (H&E×400). Endotherial cells of normal rats were lining on the tunica intima (TI) (arrow-heads) (a). Most of the medial smooth muscle cells (arrows) of the tunica media (TM) oriented horizontal to the aortic canal. Normal amount of collagen fiber and connective tissue were exhibited in the tunica adventitia (TA). Multifocal degeneration, necrosis and disorientation of smooth muscle cells (arrows) in HC rats were shown (b). Multifocal mononuclear cell infiltration in the aortic wall (arrow -heads ) was also shown. No remarkable lesions of aortic tissue was observed in HC rats treated with aqueous extracts of OS leaves (c). Endothelial cells were lining on the tunica intima (arrow-heads). Most of the medial smooth muscle cells (arrows) of the tunica media oriented horizontal to the aortic canal. Normal amount of collagen fiber and connective tissue were exhibited in the tunica adventitia.
