Antioxidant Capacity of Flavonoids in Hepatic Microsomes Is not Reflected by Antioxidant Effects In Vivo

Table 2

Abilities of polyphenol aglycones and dα-tocopherol to inhibit maximum peroxidation of hepatic microsomal preparations from vitamin E deficient rats.

Compound		Inhibition (%)
	0.1 mM	0.25 mM	0.5 mM
Quercetin	38	87	95
Kaempferol	21	88	95
Myricetin	11	67	60
Apigenin	1	1	0
Catechin	1	1	1
Morin	7	13	44
Galingin	13	88	94
Fisetin	10	68	90
dα-tocopherol	93	97	95

Peroxidation was initiated with an ascorbate/Fe²⁺/ADP complex and estimated by the formation of thiobarbituric acid substances (TBARS) as described in Section 2. Values are means of duplicate determinations.