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Oxidative Medicine and Cellular Longevity
Volume 2012 (2012), Article ID 313275, 14 pages
http://dx.doi.org/10.1155/2012/313275
Research Article

TPEN Induces Apoptosis Independently of Zinc Chelator Activity in a Model of Acute Lymphoblastic Leukemia and Ex Vivo Acute Leukemia Cells through Oxidative Stress and Mitochondria Caspase-3- and AIF-Dependent Pathways

Neuroscience Research Group, Medical Research Institute School of Medicine, University of Antioquia (UdeA), Calle 62 No. 52-59, Building 1, Laboratory 411/412, SIU, Medellin, Colombia

Received 25 September 2012; Accepted 4 November 2012

Academic Editor: Felipe Dal-Pizzol

Copyright © 2012 Miguel Mendivil-Perez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Miguel Mendivil-Perez, Carlos Velez-Pardo, and Marlene Jimenez-Del-Rio, “TPEN Induces Apoptosis Independently of Zinc Chelator Activity in a Model of Acute Lymphoblastic Leukemia and Ex Vivo Acute Leukemia Cells through Oxidative Stress and Mitochondria Caspase-3- and AIF-Dependent Pathways,” Oxidative Medicine and Cellular Longevity, vol. 2012, Article ID 313275, 14 pages, 2012. doi:10.1155/2012/313275