Coffee Polyphenols Change the Expression of STAT5B and ATF-2 Modifying Cyclin D1 Levels in Cancer Cells

Figure 1

Biological association network (BAN) of differentially expressed genes in common between CA and ICC. The list of common genes between both treatments was used to construct a BAN with the Pathway Analysis software within GeneSpring v.11.5.1. An expanded network was constructed by setting an advanced filter that included the categories of binding, expression, metabolism, promoter binding, protein modification, and regulation. Only proteins are represented. The BAN shows the node genes STAT5B and ATF-2 that were further studied.