Table 2: List of overexpressed genes in HT29 cells upon incubation with instant caffeinated coffee.

Gene symbolGene title valueFC absoluteRegulation

CALM3Calmodulin 3 (phosphorylase kinase, delta)0.0161.3Up
CDC42EP1CDC42 effector protein (Rho GTPase binding) 10.0271.3Up
FOXN3Forkhead box N30.0221.3Up
KIR2DL1Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 10.0231.3Up
ORAI2ORAI calcium release-activated calcium modulator 20.0111.3Up
RAPGEF1Rap guanine nucleotide exchange factor (GEF) 10.0221.3Up
STHSaitohin0.0311.3Up
SLC39A3Solute carrier family 39 (zinc transporter), member 30.0281.3Up
ZNF397OSZinc finger protein 397 opposite strand0.0241.3Up
ZP4Zona pellucida glycoprotein 40.0461.3Up
FGFRL1Fibroblast growth factor receptor-like 10.0351.31Up
ITGA9Integrin, alpha 90.0021.31Up
IRAK1Interleukin-1 receptor-associated kinase 10.0381.31Up
OBSL1Obscurin-like 10.0081.31Up
RPS17L4Ribosomal protein S17-like 40.0261.31Up
STAT5BSignal transducer and activator of transcription 5B0.0071.31Up
TRABDTraB domain containing0.0431.31Up
MYO9BMyosin IXB0.0411.32Up
NME7Nonmetastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)0.0371.32Up
RPS6KA4Ribosomal protein S6 kinase, 90 kDa, polypeptide 40.0141.32Up
SIRPASignal-regulatory protein alpha0.0191.32Up
TBX20T-box 200.0351.32Up
TCF20Transcription factor 20 (AR1)0.0221.32Up
ALDH3B1Aldehyde dehydrogenase 3 family, member B10.0051.33Up
BGNBiglycan0.0291.33Up
GNB4Guanine nucleotide binding-protein (G protein), b-polypeptide 40.0441.33Up
IFNA17Interferon, alpha 170.0261.33Up
KYKyphoscoliosis peptidase0.0131.33Up
SCARF1Scavenger receptor class F, member 10.0251.33Up
SERPINB8Serpin peptidase inhibitor, clade B (ovalbumin), member 80.011.33Up
FSTFollistatin0.0251.34Up
MOGAT1Monoacylglycerol O-acyltransferase 10.0091.34Up
PPARGC1APeroxisome proliferator-activated receptor gamma, coactivator 1 alpha0.0151.34Up
SUCLG2Succinate-CoA ligase, GDP-forming, beta subunit0.0111.34Up
SULT1B1Sulfotransferase family, cytosolic, 1B, member 10.0181.34Up
TBX10T-box 100.0111.34Up
ZNF503Zinc finger protein 5030.0221.34Up
HBA1Hemoglobin, alpha 10.041.35Up
MEPEMatrix, extracellular phosphoglycoprotein with ASARM motif0.0011.35Up
PPP1CBProtein phosphatase 1, catalytic subunit, beta isoform0.031.35Up
ARV1ARV1 homolog (S. cerevisiae)0.0111.36Up
BCL3B-cell CLL/lymphoma 30.0341.36Up
CTRCChymotrypsin C (caldecrin)0.0451.36Up
EPORErythropoietin receptor0.0081.37Up
HMGA1High-mobility group AT-hook 10.0391.37Up
IL19Interleukin 190.0181.38Up
ABCC12ATP-binding cassette, subfamily C (CFTR/MRP), member 126.00E-041.39Up
RAI1Retinoic acid induced 10.0171.39Up
KLF5Kruppel-like factor 5 (intestinal)0.0281.4Up
CBWD1COBW domain containing 10.0441.41Up
ASAH3N-acylsphingosine amidohydrolase (alkaline ceramidase) 30.0391.43Up
ABHD14BAbhydrolase domain containing 14B0.031.45Up
TLN1Talin 10.0491.45Up
ARHGAP23Rho GTPase-activating protein 230.0241.65Up
HINT3Histidine triad nucleotide binding protein 30.0021.77Up
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.0341.83Up
CALRCalreticulin0.0071.93Up

The table shows the list of overexpressed genes by 1.3-fold with a value obtained in cells treated with instant caffeinated coffee and includes the gene symbol for all genes, and their associated description. The ratio columns correspond to the absolute fold change in expression relative to the control group and the type of regulation (up: upregulation).