Table 5: List of underexpressed genes in HT29 cells upon incubation with caffeic acid.

Gene symbolGene title valueFC absoluteRegulation

MFSD7Major facilitator superfamily domain containing 71.00E-041.3Down
MSI2Musashi homolog 2 (Drosophila)0.0271.3Down
CDACytidine deaminase2.00E-041.31Down
DEFB1Defensin, beta 10.0261.31Down
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase, type I, alpha0.0271.31Down
ZDHHC20Zinc finger, DHHC-type containing 200.0051.31Down
ZDHHC21Zinc finger, DHHC-type containing 210.0161.31Down
SLC4A7Solute carrier family 4, member 70.02491.32Down
CEACAM1Carcinoembryonic antigen-related cell adhesion molecule 10.04591.32Down
PDZRN3PDZ domain containing RING finger 30.0021.32Down
WDR62WD repeat domain 620.0051.32Down
FAM76BFamily with sequence similarity 76, member B0.0361.32Down
TCF21Transcription factor 210.0291.33Down
TBL1XR1Transducin (beta)-like 1 X-linked receptor 16.00E-041.33Down
CLK4CDC-like kinase 40.0211.33Down
CYP2A13Cytochrome P450, family 2, subfamily A, polypeptide 130.0091.34Down
CXCR4Chemokine (C-X-C motif) receptor 40.04881.34Down
ATF2Activating transcription factor 20.01581.35Down
PDE10APhosphodiesterase 10A0.031.35Down
METT10DMethyltransferase 10 domain containing0.0031.35Down
PRMT2Protein arginine methyltransferase 27.00E-041.36Down
GLSGlutaminase5.70E-041.37Down
SLC38A5Solute carrier family 38, member 50.0431.37Down
TINAGTubulointerstitial nephritis antigen0.0431.38Down
AQP1Aquaporin 1 (Colton blood group)0.02211.4Down
JMJD6Jumonji domain containing 60.0041.4Down
SAP30LSAP30-like0.0211.4Down
FGD4FYVE, RhoGEF, and PH domain containing 40.0261.52Down
S100A2S100 calcium-binding protein A20.0051.53Down
CTSZCathepsin Z0.0451.53Down
SLC4A4Solute carrier family 4, member 49.00E-041.54Down
AGR3Anterior gradient homolog 3 (Xenopus laevis)0.0111.69Down

The table shows the list of underexpressed genes by 1.3-fold with a value obtained in cells treated with caffeic acid and includes the gene symbol for all genes, their associated description. The ratio columns correspond to the absolute fold change in expression relative to the control group and the type of regulation (down: downregulation).