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Oxidative Medicine and Cellular Longevity
Volume 2012 (2012), Article ID 458276, 15 pages
http://dx.doi.org/10.1155/2012/458276
Review Article

Therapeutic Targeting of Redox Signaling in Myofibroblast Differentiation and Age-Related Fibrotic Disease

1Department of Experimental Urology, Medical University of Innsbruck, 6020 Innsbruck, Austria
2Institute for Biomedical Aging Research, Austrian Academy of Sciences, 6020 Innsbruck, Austria

Received 29 June 2012; Accepted 18 September 2012

Academic Editor: Paula Ludovico

Copyright © 2012 Natalie Sampson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [10 citations]

The following is the list of published articles that have cited the current article.

  • Pedro Cisternas, Juan P. Henriquez, Enrique Brandan, and Nibaldo C. Inestrosa, “Wnt Signaling in Skeletal Muscle Dynamics: Myogenesis, Neuromuscular Synapse and Fibrosis,” Molecular Neurobiology, 2013. View at Publisher · View at Google Scholar
  • Andrea Dueregger, Fabian Guggenberger, Jan Barthelmes, Günther Stecher, Markus Schuh, Daniel Intelmann, Gudrun Abel, Jutta Haunschild, Helmut Klocker, Reinhold Ramoner, and Natalie Sampson, “Attenuation of nucleoside and anti-cancer nucleoside analog drug uptake in prostate cancer cells by Cimicifuga racemosa extract BNO-1055,” Phytomedicine, 2013. View at Publisher · View at Google Scholar
  • Alessandro Siani, and Nicola Tirelli, “Myofibroblast differentiation: main features, biomedical relevance and the role of Reactive Oxygen Species,” Antioxidants & Redox Signaling, pp. 131126162643002, 2013. View at Publisher · View at Google Scholar
  • Olubukola Babalola, Andrew Mamalis, Hadar Lev-Tov, and Jared Jagdeo, “NADPH oxidase enzymes in skin fibrosis: molecular targets and therapeutic agents,” Archives of Dermatological Research, vol. 306, no. 4, pp. 313–330, 2013. View at Publisher · View at Google Scholar
  • Martin Hermann, Eugen Plas, Helmut Klocker, Peter Berger, Georg Schaefer, Natalie Sampson, Christoph Zenzmaier, and Martin Heitz, “Stromal Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) Is Elevated in the Diseased Human Prostate and Promotes ex Vivo Fibroblast-to-Myofibroblast Differentiation,” Endocrinology, vol. 154, no. 8, pp. 2586–2599, 2013. View at Publisher · View at Google Scholar
  • Yueh-Te Lin, Jhih-Sian Chen, Ming-Heng Wu, I-Shan Hsieh, Chen-Hsien Liang, Cheng-Lung Hsu, Tse-Ming Hong, and Yuh-Ling Chen, “Galectin-1 Accelerates Wound Healing by Regulating the Neuropilin-1/Smad3/NOX4 Pathway and ROS Production in Myofibroblasts,” Journal of Investigative Dermatology, 2014. View at Publisher · View at Google Scholar
  • Zhi-Wei Ye, Jie Zhang, Danyelle M. Townsend, and Kenneth D. Tew, “Oxidative Stress, Redox Regulation and Diseases of Cellular Differentiation,” Biochimica et Biophysica Acta (BBA) - General Subjects, 2014. View at Publisher · View at Google Scholar
  • Anjali Shroff, Andrew Mamalis, and Jared Jagdeo, “Oxidative Stress and Skin Fibrosis,” Current Pathobiology Reports, 2014. View at Publisher · View at Google Scholar
  • Fan Jiang, Guei-Sheung Liu, Gregory J. Dusting, and Elsa C. Chan, “NADPH oxidase-dependent redox signaling in TGF-β-mediated fibrotic responses,” Redox Biology, 2014. View at Publisher · View at Google Scholar
  • Natalie Sampson, Peter Berger, and Christoph Zenzmaier, “Redox Signaling as a Therapeutic Target to Inhibit Myofibroblast Activation in Degenerative Fibrotic Disease,” BioMed Research International, vol. 2014, pp. 1–14, 2014. View at Publisher · View at Google Scholar