Cholesterol-Lowering Effect of Allicin on Hypercholesterolemic ICR Mice

Table 2

Serum parameters after 12-week allicin administration (𝑛=6, mM).

Parameter	5 mg/kg	10 mg/kg	20 mg/kg	Controlc	Normal (regular diet)
	High-cholesterol diet (allicin administered)
TC	43.91±4.21^b	32.91±1.34^b	37.45±0.80^b	57.82±3.51^b	32.99±0.55
TG	1.66±0.34^a	1.33±0.11^b	1.89±0.19^b	2.11±0.35^b	1.04±0.23
GLU	8.73±0.49	8.22±1.52	8.10±0.14	14.08±3.16^b	8.38±0.75
HDL-C	1.25±0.20^a	1.71±0.59	1.60±0.45	1.61±0.16	1.94±0.22
LDL-C	1.06±0.52^a	1.04±0.22^a	0.80±0.15^a	1.83±0.50	1.57±0.43

The data are mean ± S.D. and significantly different at ^a𝑃<0.05 and ^b𝑃<0.01 by the unpaired Student's t-test.
TC: total cholesterol, TG: triglyceride, GLU: plasma glucose, HDL-C: high-density lipoprotein cholesterol, LDL-C: low-density lipoprotein cholesterol.
cThe high cholesterol control group, 200 μL PBS (pH 7.4) was served instead of allicin as a negative control.