Cardiac Response to Chronic Intermittent Hypoxia with a Transition from Adaptation to Maladaptation: The Role of Hydrogen Peroxide

Table 2

Effect of CIH on cardiac functions.

Authors	Strains	Exposure time	Effects	Reference
Naghshin et al.	C57BL/6J mice	4 wks	Protective effects	[15]
Lee et al.	SD rats	1, 4 days and 1, 2 wks	1, 4 days: protective effects 1, 2 wks: deleterious effects	[16]
Campen et al.	C57BL/6J mice		Deleterious effects	[17]
Chen et al.	Male SD rats	5 wks	Deleterious effects	[18, 19]
Williams et al.	Male SD rats	5 wks, 6 wks	Deleterious effects	[20]
Chen et al.	Male SD rats	10 days	Deleterious effects	[21]
Yin et al.	FVB mice	4 wks and 8 wks	Deleterious effects	[22]
Yang et al.	Patients	4 wks and 8 wks	Deleterious effects	[23]

*wks: weeks.