- About this Journal
- Abstracting and Indexing
- Aims and Scope
- Annual Issues
- Article Processing Charges
- Articles in Press
- Author Guidelines
- Bibliographic Information
- Citations to this Journal
- Contact Information
- Editorial Board
- Editorial Workflow
- Free eTOC Alerts
- Publication Ethics
- Reviewers Acknowledgment
- Submit a Manuscript
- Subscription Information
- Table of Contents
Oxidative Medicine and Cellular Longevity
Volume 2012 (2012), Article ID 628352, 9 pages
Low-Frequency Fatigue as an Indicator of Eccentric Exercise-Induced Muscle Injury: The Role of Vitamin E
1Exercise Physiology and Biochemistry Laboratory, Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, 62110 Serres, Greece
2Department of Physical Education and Sport Science, University of Thessaly, Karies, 42100 Trikala, Greece
3Laboratory of Exercise, Health and Human Performance, Research Center, European University of Cyprus, 2404 Nicosia, Cyprus
4Laboratory of Physiology, Faculty of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
5Laboratory of Physiology, Department of Physical Education and Sports Science, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
Received 7 April 2012; Accepted 14 June 2012
Academic Editor: Chad M. Kerksick
Copyright © 2012 Antonios Kyparos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- R. B. Armstrong, R. W. Ogilvie, and J. A. Schwane, “Eccentric exercise-induced injury to rat skeletal muscle,” Journal of Applied Physiology Respiratory Environmental and Exercise Physiology, vol. 54, no. 1, pp. 80–93, 1983.
- P. M. Clarkson and M. J. Hubal, “Exercise-induced muscle damage in humans,” American Journal of Physical Medicine and Rehabilitation, vol. 81, no. 11, supplement, pp. S52–S69, 2002.
- D. J. Newham, G. McPhail, K. R. Mills, and R. H. T. Edwards, “Ultrastructural changes after concentric and eccentric contractions of human muscle,” Journal of the Neurological Sciences, vol. 61, no. 1, pp. 109–122, 1983.
- R. W. Ogilvie, R. B. Armstrong, K. E. Baird, and C. L. Bottoms, “Lesions in the rat muscle following eccentrically biased exercise,” American Journal of Anatomy, vol. 182, no. 4, pp. 335–346, 1988.
- C. D. Balnave and D. G. Allen, “Intracellular calcium and force in single mouse muscle fibres following repeated contractions with stretch,” Journal of Physiology, vol. 488, no. 1, pp. 25–36, 1995.
- C. T. M. Davies and M. J. White, “Muscle weakness following eccentric work in man,” Pflugers Archiv European Journal of Physiology, vol. 392, no. 2, pp. 168–171, 1981.
- G. S. Lynch, C. J. Fary, and D. A. Williams, “Quantitative measurement of resting skeletal muscle [Ca2+] following acute and long-term downhill running exercise in mice,” Cell Calcium, vol. 22, no. 5, pp. 373–383, 1997.
- G. L. Warren, D. A. Lowe, and R. B. Armstrong, “Measurement tools used in the study of eccentric contraction-induced injury,” Sports Medicine, vol. 27, no. 1, pp. 43–59, 1999.
- H. Westerblad and D. G. Allen, “Recent advances in the understanding of skeletal muscle fatigue,” Current Opinion in Rheumatology, vol. 14, no. 6, pp. 648–652, 2002.
- D. A. Jones, D. J. Newham, and C. Torgan, “Mechanical influences on long-lasting human muscle fatigue and delayed-onset pain,” Journal of Physiology, vol. 412, pp. 415–427, 1989.
- D. J. Newham, K. R. Mills, B. M. Quigley, and R. H. T. Edwards, “Pain and fatigue after concentric and eccentric muscle contractions,” Clinical Science, vol. 64, no. 1, pp. 55–62, 1983.
- E. W. Yeung, J. P. Bourreau, D. G. Allenand, and H. J. Ballard, “Effect of eccentric contraction-induced injury on force and intracellular pH in rat skeletal muscles,” Journal of Applied Physiology, vol. 92, no. 1, pp. 93–99, 2002.
- K. K. McCully and J. A. Faulkner, “Injury to skeletal muscle fibers of mice following lengthening contractions,” Journal of Applied Physiology, vol. 59, no. 1, pp. 119–126, 1985.
- E. A. Abou Salem, N. Fujimaki, and H. Ishikawa, “Formation of unique vacuoles in tenotomized rat soleus muscle fibers,” Archives of Histology and Cytology, vol. 64, no. 3, pp. 247–257, 2001.
- R. H. T. Edwards, D. K. Hill, D. A. Jones, and P. A. Merton, “Fatigue of long duration in human skeletal muscle after exercise,” Journal of Physiology, vol. 272, no. 3, pp. 769–778, 1977.
- G. L. Warren, C. P. Ingalls, D. A. Lowe, and R. B. Armstrong, “Excitation-contraction uncoupling: major role in contraction-induced muscle injury,” Exercise and Sport Sciences Reviews, vol. 29, no. 2, pp. 82–87, 2001.
- G. L. Warren, D. A. Lowe, D. A. Hayes, C. J. Karwoski, B. M. Prior, and R. B. Armstrong, “Excitation failure in eccentric contraction-induced injury of mouse soleus muscle,” Journal of Physiology, vol. 468, pp. 487–499, 1993.
- H. Westerblad, S. Duty, and D. G. Allen, “Intracellular calcium concentration during low-frequency fatigue in isolated single fibers of mouse skeletal muscle,” Journal of Applied Physiology, vol. 75, no. 1, pp. 382–388, 1993.
- E. W. Yeung, C. D. Balnave, H. J. Ballard, J. P. Bourreau, and D. G. Allen, “Development of T-tubular vacuoles in eccentrically damaged mouse muscle fibres,” Journal of Physiology, vol. 540, no. 2, pp. 581–592, 2002.
- R. J. Bloomer, “The role of nutritional supplements in the prevention and treatment of resistance exercise-induced skeletal muscle injury,” Sports Medicine, vol. 37, no. 6, pp. 519–532, 2007.
- M. J. Jackson, M. Khassaf, A. Vasilaki, F. McArdle, and A. McArdle, “Vitamin E and the oxidative stress of exercise,” Annals of the New York Academy of Sciences, vol. 1031, pp. 158–168, 2004.
- J. M. Sacheck and J. B. Blumberg, “Role of vitamin E and oxidative stress in exercise,” Nutrition, vol. 17, no. 10, pp. 809–814, 2001.
- G. W. Burton and K. U. Ingold, “Vitamin E as an in vitro and in vivo antioxidant,” Annals of the New York Academy of Sciences, vol. 570, pp. 7–22, 1989.
- A. N. Erin, M. M. Spirin, L. V. Tabidze, and V. E. Kagan, “Formation of α-tocopherol complexes with fatty acids. A hypothetical mechanism of stabilization of biomembranes by vitamin E,” Biochimica et Biophysica Acta, vol. 774, no. 1, pp. 96–102, 1984.
- A. C. Howard, A. K. McNeil, and P. L. McNeil, “Promotion of plasma membrane repair by vitamin e,” Nature Communications, vol. 2, no. 1, Article ID 597, 2011.
- S. Urano, M. Matsuo, T. Sakanaka et al., “Mobility and molecular orientation of vitamin E in liposomal membranes as determined by 19F NMR and fluorescence polarization techniques,” Archives of Biochemistry and Biophysics, vol. 303, no. 1, pp. 10–14, 1993.
- D. M. Bailey, C. Williams, J. A. Betts, D. Thompson, and T. L. Hurst, “Oxidative stress, inflammation and recovery of muscle function after damaging exercise: effect of 6-week mixed antioxidant supplementation,” European Journal of Applied Physiology, vol. 111, no. 6, pp. 925–936, 2011.
- L. J. Beaton, D. A. Allan, M. A. Tarnopolsky, P. M. Tiidus, and S. M. Phillips, “Contraction-induced muscle damage is unaffected by vitamin E supplementation,” Medicine and Science in Sports and Exercise, vol. 34, no. 5, pp. 798–805, 2002.
- R. J. Bloomer, A. H. Goldfarb, M. J. McKenzie, T. You, and L. Nguyen, “Effects of antioxidant therapy in women exposed to eccentric exercise,” International Journal of Sport Nutrition and Exercise Metabolism, vol. 14, no. 4, pp. 377–388, 2004.
- P. Jakeman and S. Maxwell, “Effect of antioxidant vitamin supplementation on muscle function after eccentric exercise,” European Journal of Applied Physiology and Occupational Physiology, vol. 67, no. 5, pp. 426–430, 1993.
- A. A. Theodorou, M. G. Nikolaidis, V. Paschalis et al., “No effect of antioxidant supplementation on muscle performance and blood redox status adaptations to eccentric training,” American Journal of Clinical Nutrition, vol. 93, no. 6, pp. 1373–1383, 2011.
- A. Kyparos, S. Sotiriadou, V. Mougios et al., “Effect of 5-day vitamin E supplementation on muscle injury after downhill running in rats,” European Journal of Applied Physiology, vol. 111, no. 10, pp. 2557–2569, 2011.
- J. H. Van Der Meulen, A. McArdle, M. J. Jackson, and J. A. Faulkner, “Contraction-induced injury to the extensor digitorum longus muscles of rats: the role of vitamin E,” Journal of Applied Physiology, vol. 83, no. 3, pp. 817–823, 1997.
- J. A. Warren, R. R. Jenkins, L. Packer, E. H. Witt, and R. B. Armstrong, “Elevated muscle vitamin E does not attenuate eccentric exercise-induced muscle injury,” Journal of Applied Physiology, vol. 72, no. 6, pp. 2168–2175, 1992.
- A. Shafat, P. Butler, R. L. Jensen, and A. E. Donnelly, “Effects of dietary supplementation with vitamins C and E on muscle function during and after eccentric contractions in humans,” European Journal of Applied Physiology, vol. 93, no. 1-2, pp. 196–202, 2004.
- F. Eusebi, R. Miledi, and T. Takahashi, “Calcium transients in mammalian muscles,” Nature, vol. 284, no. 5756, pp. 560–561, 1980.
- D. A. Jones, “High- and low-frequency fatigue revisited,” Acta Physiologica Scandinavica, vol. 156, no. 3, pp. 265–270, 1996.
- R. B. Armstrong, “Initial events in exercise-induced muscular injury,” Medicine and Science in Sports and Exercise, vol. 22, no. 4, pp. 429–435, 1990.
- J. Hidalgo, L. Campmany, M. Borras, J. S. Garvey, and A. Armario, “Metallothionein response to stress in rats: role in free radical scavenging,” American Journal of Physiology, vol. 255, no. 4, part 1, pp. E518–E524, 1988.
- S. Kovacheva and S. R. Ribarov, “Lipid peroxidation in lung of rat stressed by immobilization: effects of vitamin E supplementation,” Lung, vol. 173, no. 4, pp. 255–263, 1995.
- S. Sotiriadou, A. Kyparos, M. Albani et al., “Soleus muscle force following downhill running in ovariectomized rats treated with estrogen,” Applied Physiology, Nutrition and Metabolism, vol. 31, no. 4, pp. 449–459, 2006.
- H. Takekura, N. Fujinami, T. Nishizawa, H. Ogasawara, and N. Kasuga, “Eccentric exercise-induced morphological changes in the membrane systems involved in excitation-contraction coupling in rat skeletal muscle,” Journal of Physiology, vol. 533, no. 2, pp. 571–583, 2001.
- D. W. Nierenberg and S. L. Nann, “A method for determining concentrations of retinol, tocopherol, and five carotenoids in human plasma and tissue samples,” American Journal of Clinical Nutrition, vol. 56, no. 2, pp. 417–426, 1992.
- J. Cohen, Statistical Power Analysis for the Behavioral Sciences, Lawrence Erlbaum, Hillsdale, NJ, USA, 1998.
- A. Kyparos, C. Matziari, M. Albani, G. Arsos, S. Sotiriadou, and A. Deligiannis, “A decrease in soleus muscle force generation in rats after downhill running,” Canadian Journal of Applied Physiology, vol. 26, no. 4, pp. 323–335, 2001.
- C. P. Ingalls, G. L. Warren, J. H. Williams, C. W. Ward, and R. B. Armstrong, “E-C coupling failure in mouse EDL muscle after in vivo eccentric contractions,” Journal of Applied Physiology, vol. 85, no. 1, pp. 58–67, 1998.
- J. L. Vergara, S. I. Rapoport, and V. Nassar Gentina, “Fatigue and posttetanic potentiation in single muscle fibers of the frog,” American Journal of Physiology, vol. 232, no. 5, pp. C185–C190, 1977.
- H. Westerblad and D. G. Allen, “Changes of myoplasmic calcium concentration during fatigue in single mouse muscle fibers,” Journal of General Physiology, vol. 98, no. 3, pp. 615–635, 1991.
- D. A. Essig and T. M. Nosek, “Muscle fatigue and induction of stress protein genes: a dual function of reactive oxygen species?” Canadian Journal of Applied Physiology, vol. 22, no. 5, pp. 409–428, 1997.
- G. D. Lamb and H. Westerblad, “Acute effects of reactive oxygen and nitrogen species on the contractile function of skeletal muscle,” Journal of Physiology, vol. 589, no. 9, pp. 2119–2127, 2011.
- H. Westerblad and D. G. Allen, “Emerging roles of ROS/RNS in muscle function and fatigue,” Antioxidants and Redox Signaling, vol. 15, no. 9, pp. 2487–2499, 2011.
- G. D. Lamb, “Excitation-contraction coupling and fatigue mechanisms in skeletal muscle: studies with mechanically skinned fibres,” Journal of Muscle Research and Cell Motility, vol. 23, no. 1, pp. 81–91, 2002.
- G. D. Lamb, “Mechanisms of excitation-contraction uncoupling relevant to activity-induced muscle fatigue,” Applied Physiology, Nutrition and Metabolism, vol. 34, no. 3, pp. 368–372, 2009.
- T. You, A. H. Goldfarb, R. J. Bloomer, L. Nguyen, X. Sha, and M. J. McKenzie, “Oxidative stress response in normal and antioxidant supplemented rats to a downhill run: changes in blood and skeletal muscles,” Canadian Journal of Applied Physiology, vol. 30, no. 6, pp. 677–689, 2005.
- M. Meydani, W. J. Evans, G. Handelman et al., “Protective effect of vitamin E on exercise-induced oxidative damage in young and older adults,” American Journal of Physiology, vol. 264, no. 5, pp. R992–R998, 1993.
- M. G. Nikolaidis, A. Kyparos, C. Spanou, V. Paschalis, A. A. Theodorou, and I. S. Vrabas, “Redox biology of exercise: an integrative and comparative consideration of some overlooked issues,” The Journal of Experimental Biology, vol. 215, no. 10, pp. 1615–1625, 2012.