Schizandrin, an Antioxidant Lignan from Schisandra chinensis, Ameliorates Aβ_1–42-Induced Memory Impairment in Mice

Table 1

Effects of SCH on locomotor activity of A𝛽_1-42-induced memory impairment in mice (𝑛= 9-10).

Group	Dose (mg/kg)	Locomotor activity (cm/10 min, mean ± S.E.M.)
Sham	—	4923.37 ± 399.171
Control	—	5205.88 ± 213.25
DPZ	0.65	5293.63 ± 457.79
SCH	4	4685.69 ± 406.90
SCH	12	5035.32 ± 757.24
SCH	36	5082.48 ± 281.53

Mice in sham-operated and control groups were treated with distilled water orally (20 mL/kg). Values were mean ± S.E.M. and analyzed by one-way ANOVA followed by LSD test for multiple comparisons.