Blockade of TGF- 1 Signalling Inhibits Cardiac NADPH Oxidase Overactivity in Hypertensive Rats
Figure 5
Effect of P144 on cardiac collagen type I expression. (a) mRNA levels of collagen type I expressed as a ratio of gene to 18S values from rat heart. (b) Expression of the collagen type I protein relative to α-tubulin in the rat heart. Representative western blot of the four groups of rats are shown at the upper part. Histograms represent mean ± SEM (). V-WKY means vehicle-treated normotensive rat; P144-WKY, P144-treated WKY rat; V-SHR, vehicle-treated spontaneously hypertensive rat; P144-SHR, P144-treated SHR. * and * versus the other groups.
