Table 2: Body weight and AGEs Levels.

GroupTreatmentBody weightSerum AGEs (ng/mL)Cerebral AGEs (ng/mg prot)
PretreatmentPosttreatment

IYoung control
IID-gal (100 mg/kg) * *
IIID-gal + PP (500 mg/kg)
IVD-gal + PP (1000 mg/kg)
VD-gal + PP (1500 mg/kg)
VID-gal + AG (100 mg/kg)

Note. C57BL/6J female mice (5-month-old, in each group) were treated daily with PBS (s.c, young control), D-galactose (D-gal, 100 mg/kg, s.c), D-gal (100 mg/kg, s.c) with pine pollen (PP, 500, 1000, 1500 mg/kg, ig) and aminoguanidine (AG, 100 mg/kg, ig). AGEs levels at the end of the treatment were determined by a quantitative AGEs-ELISA kit. Statistical significant difference: , versus I; , versus II.