Protective Effects of Aspirin from Cardiac Hypertrophy and Oxidative Stress in Cardiomyopathic Hamsters
Figure 3
(a) Representative cross-sectional tissue slices of hearts stained with picrosirius red show minimal fibrosis in control (Cntrl) and importantly increased fibrosis in 350-day-old cardiomyopathic hearts (CM). ASA treatment significantly reduced the cardiomyotic fibrosis in the CM hamsters (CM + ASA), but did not show any effect on control (Cntrl + ASA), (b) Percentage of the tissue occupied by fibrosis in whole ventricular section of 350-day-old untreated or ASA-treated control or cardiomyopathic hamsters. ** versus control, + versus CM hamsters.
