Prevention of Diabetic Nephropathy by Sulforaphane: Possible Role of Nrf2 Upregulation and Activation

<table>SFN upregulated renal expression of Nrf2 and its downstream genes at mRNA level.  Nrf2 (a) and its downstream genes, NQO1 (b), HO-1 (c), SOD1 (d), SOD2 (e), and CAT (f) expression at mRNA level were detected by RT-PCR. Data were presented as means ± SD (<svg height="11.225" id="M6" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> at least). (*<i>P</i> &lt; 0.05 versus control; <sup>#</sup><i>P</i> &lt;  0.05 versus DM group).</table>

Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Prevention of Diabetic Nephropathy by Sulforaphane: Possible Role of Nrf2 Upregulation and Activation 