Simvastatin Attenuates Contrast-Induced Nephropathy through Modulation of Oxidative Stress, Proinflammatory Myeloperoxidase, and Nitric Oxide

Figure 1

Effect of Simvastatin treatment on blood urea nitrogen, serum creatinine, and calcium in a rat model of contrast media-induced nephropathy. Values are ± SEM. *𝑃<0.05, **𝑃<0.01 as compared with control group, and ^#𝑃<0.05, ^##𝑃<0.01 versus glycerol + CM using Tukey's test. CM: contrast media; SSTN: simvastatin, 15, 30, and 60 mg/kg.