Simvastatin Attenuates Contrast-Induced Nephropathy through Modulation of Oxidative Stress, Proinflammatory Myeloperoxidase, and Nitric Oxide

Figure 2

Effect of simvastatin on TBARS, NO, GSH, and MPO in a rat model of contrast media-induced nephropathy. Values are mean ± SEM. *𝑃<0.05, **𝑃<0.01 as compared to control group and ^#𝑃<0.05, ^##𝑃<0.01, and ^###𝑃<0.001 versus glycerol + CM group using Tukey's test. CM: contrast media; SSTN: simvastatin 10, 30, and 60 mg/kg.