Table 2: Effect of simvastatin on tubular injury scores in a rat model of CM nephropathy.

GroupsTubular dilatation Tubular vacuolationTubular necrosisKidney wt/Body ratio (%)

Control0000.33 0.01
Glycerol *** 0.6 0.20*0.70 0.18**0.58 0.04***
CM + glycerol 3.4 0.32***2.9 0.29***3.0 0.26***0.61 0.04***
CM + glycerol + SSTN 152.3 0.28#1.0 0.01###0.40 0.20##0.50 0.03#
CM + glycerol + SSTN 301.9 0.22###0.9 0.01###0 0###0.48 0.03#
CM + glycerol + SSTN 601.2 0.2###0.4 0.24###00.47 0.03##
SSTN 60 0000.31 0.00

Values are mean ± SEM. * , ** , and *** versus control group; # , ## , and ### versus glycerol + CM group using Tukey’s test.
High scores indicate severe injury.