The Antioxidant Mechanisms Underlying the Aged Garlic Extract- and S-Allylcysteine-Induced Protection

Table 3

Pharmacokinetic parameters for oral and i.v. administration of SAC in the serum of rats.^A

Parameter	Oral administration	i.v. administration
Distribution volume (𝑉𝑑)	1.2 L	1.3 L
Elimination half-life (𝑇1/2𝛽)	2.7 h	2.6 h
Total clearance	0.3 L/h	0.3 L/h
Peak concentration (𝐶max)	100.1 mg/L at 30 min
AUC0–t value	293.5 mg·h/L	322.6 mg·h/L

^ASynthesized from [19]. AUC_0–t : area under the plasma concentration versus time curve from time zero to the last quantifiable concentration.