Biomarkers of Antioxidant Status, Inflammation, and Cartilage Metabolism Are Affected by Acute Intense Exercise but Not Superoxide Dismutase Supplementation in Horses

Table 3

Exercise trial: interferon γ (IFNγ), interleukin-1β (IL-1β), and interleukin-10 (IL-10) relative mRNA transcript (RMT) in peripheral blood of Standardbred mares before exercise (Pre), 30 min after exercise (Post), 2 h, and 24 h Post. qRT-PCR data are presented as the mean fold change in target gene expression ± SE. Means without a common superscript differ between sample times (^a,b𝑃<0.05; ^x,y𝑃<0.1). No TRT effects were detected.

	Pre		30 min Post		2 h Post		24 h Post
	TRT	CON	TRT	CON	TRT	CON	TRT	CON
IFNγ, RMT	1.1±0.2^a	1.2±0.2^a	2.7±1.1^b	3.6±1.9^b	0.9±0.1^a	1.1±0.3^a	1.3±0.3^a	1.2±0.3^a
IL-1β, RMT	1.2±0.2^a	2.1±1.0^a	1.1±0.2^a	1.2±0.2^a	8.2±3.3^b	3.8±0.3^b	1.4±0.2^a	1.8±0.2^a
IL-10, RMT	1.6±0.5^x	2.0±0.5^x	3.5±1.6^y	2.5±0.7^y	2.3±0.6^x	2.3±0.8^x	1.4±0.4^x	1.2±0.3^x