- About this Journal
- Abstracting and Indexing
- Aims and Scope
- Annual Issues
- Article Processing Charges
- Articles in Press
- Author Guidelines
- Bibliographic Information
- Citations to this Journal
- Contact Information
- Editorial Board
- Editorial Workflow
- Free eTOC Alerts
- Publication Ethics
- Reviewers Acknowledgment
- Submit a Manuscript
- Subscription Information
- Table of Contents
Oxidative Medicine and Cellular Longevity
Volume 2012 (2012), Article ID 981561, 9 pages
The Role of Metal Regulatory Proteins in Brain Oxidative Stress: A Tutorial
Department of Psychology, University of Nebraska at Kearney, Kearney, NE 68849, USA
Received 14 September 2012; Revised 5 November 2012; Accepted 8 November 2012
Academic Editor: Cinzia Signorini
Copyright © 2012 Wayne Briner. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- K. Oettl and R. E. Stauber, “Physiological and pathological changes in the redox state of human serum albumin critically influence its binding properties,” British Journal of Pharmacology, vol. 151, no. 5, pp. 580–590, 2007.
- L. Turell, S. Carballal, H. Botti, R. Radi, and B. Alvarez, “Oxidation of the albumin thiol to sulfenic acid and its implications in the intravascular compartment,” Brazilian Journal of Medical and Biological Research, vol. 42, no. 4, pp. 305–311, 2009.
- A. E. Finefrock, A. I. Bush, and P. M. Doraiswamy, “Current status of metals as therapeutic targets in Alzheimer's disease,” Journal of the American Geriatrics Society, vol. 51, no. 8, pp. 1143–1148, 2003.
- C. J. Maynard, A. I. Bush, C. L. Masters, R. Cappai, and Q.-X. Li, “Metals and amyloid-β in Alzheimer's disease,” International Journal of Experimental Pathology, vol. 86, no. 3, pp. 147–159, 2005.
- H. Zheng and E. H. Koo, “Biology and pathophysiology of the amyloid precursor protein,” Molecular Neurodegeneration, vol. 6, no. 1, article 27, 2011.
- M. T. Kuo, H. H. W. Chen, I. S. Song, N. Savaraj, and T. Ishikawa, “The roles of copper transporters in cisplatin resistance,” Cancer and Metastasis Reviews, vol. 26, no. 1, pp. 71–83, 2007.
- E. D. Harris, “Copper homeostasis: the role of cellular transporters,” Nutrition Reviews, vol. 59, no. 9, pp. 281–285, 2001.
- S. Lutsenko, R. Tsivkovskii, and J. M. Walker, “Functional properties of the human copper-transporting ATPase ATP7B (the Wilson's disease protein) and regulation by metallochaperone Atox1,” Annals of the New York Academy of Sciences, vol. 986, pp. 204–211, 2003.
- S. D. P. Moore, K. E. Helmle, L. M. Prat, and D. W. Cox, “Tissue localization of the copper chaperone ATOX1 and its potential role in disease,” Mammalian Genome, vol. 13, no. 10, pp. 563–568, 2002.
- A.-M. Florea and D. Büsselberg, “Anti-cancer drugs interfere with intracellular calcium signaling,” NeuroToxicology, vol. 30, no. 5, pp. 803–810, 2009.
- B. A. Simms and G. W. Zamponi, “Trafficking and stability of voltage-gated calcium channels,” Cellular and Molecular Life Sciences, vol. 69, no. 6, pp. 843–856, 2012.
- A. Malasics, D. Boda, M. Valiskó, D. Henderson, and D. Gillespie, “Simulations of calcium channel block by trivalent cations: Gd3+ competes with permeant ions for the selectivity filter,” Biochimica et Biophysica Acta, vol. 1798, no. 11, pp. 2013–2021, 2010.
- M. Paradis, J. Gagné, M. A. Mateescu, and J. Paquin, “The effects of nitric oxide-oxidase and putative glutathione-peroxidase activities of ceruloplasmin on the viability of cardiomyocytes exposed to hydrogen peroxide,” Free Radical Biology and Medicine, vol. 49, no. 12, pp. 2019–2027, 2010.
- N. Shukla, J. Maher, J. Masters, G. D. Angelini, and J. Y. Jeremy, “Does oxidative stress change ceruloplasmin from a protective to a vasculopathic factor?” Atherosclerosis, vol. 187, no. 2, pp. 238–250, 2006.
- T. R. Golden and M. Patel, “Catalytic antioxidants and neurodegeneration,” Antioxidants and Redox Signaling, vol. 11, no. 3, pp. 555–569, 2009.
- J. F. Eisses and J. H. Kaplan, “The mechanism of copper uptake mediated by human CTR1: a mutational analysis,” Journal of Biological Chemistry, vol. 280, no. 44, pp. 37159–37168, 2005.
- J. Lee, J. R. Prohaska, and D. J. Thiele, “Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development,” Proceedings of the National Academy of Sciences of the United States of America, vol. 98, no. 12, pp. 6842–6847, 2001.
- Y. Nose, B. E. Kim, and D. J. Thiele, “Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function,” Cell Metabolism, vol. 4, no. 3, pp. 235–244, 2006.
- P. A. Sharp, “Ctr1 and its role in body copper homeostasis,” International Journal of Biochemistry and Cell Biology, vol. 35, no. 3, pp. 288–291, 2003.
- E. D. Harris, “Cellular copper transport and metabolism,” Annual Review of Nutrition, vol. 20, pp. 291–310, 2000.
- S. La Fontaine and J. F. B. Mercer, “Trafficking of the copper-ATPases, ATP7A and ATP7B: role in copper homeostasis,” Archives of Biochemistry and Biophysics, vol. 463, no. 2, pp. 149–167, 2007.
- J. R. Prohaska and A. A. Gybina, “Intracellular copper transport in mammals,” Journal of Nutrition, vol. 134, no. 5, pp. 1003–1006, 2004.
- M. Solioz, “Copper pumping ATPases: common concepts in bacteria and man,” FEBS Letters, vol. 346, no. 1, pp. 44–47, 1994.
- N. C. Andrews, “Metal transporters and disease,” Current Opinion in Chemical Biology, vol. 6, no. 2, pp. 181–186, 2002.
- M. P. Mims and J. T. Prchal, “Divalent metal transporter 1,” Hematology, vol. 10, no. 4, pp. 339–345, 2005.
- T. Moos and E. H. Morgan, “The metabolism of neuronal iron and its pathogenic role in neurological disease review,” Annals of the New York Academy of Sciences, vol. 1012, pp. 14–26, 2004.
- G. Balla, H. S. Jacob, J. Balla et al., “Ferritin: a cytoprotective antioxidant strategem of endothelium,” Journal of Biological Chemistry, vol. 267, no. 25, pp. 18148–18153, 1992.
- G. Cairo, L. Tacchini, G. Pogliaghi, E. Anzon, A. Tomasi, and A. Bernelli-Zazzera, “Induction of ferritin synthesis by oxidative stress. Transcriptional and post-transcriptional regulation by expansion of the “free” iron pool,” Journal of Biological Chemistry, vol. 270, no. 2, pp. 700–703, 1995.
- C. E. Thomas, L. A. Morehouse, and S. D. Aust, “Ferritin and superoxide-dependent lipid peroxidation,” The Journal of Biological Chemistry, vol. 260, no. 6, pp. 3275–3280, 1985.
- F. M. Torti and S. V. Torti, “Regulation of ferritin genes and protein,” Blood, vol. 99, no. 10, pp. 3505–3516, 2002.
- T. Müller and W. Kuhn, “Homocysteine levels after acute levodopa intake in patients with Parkinson's disease,” Movement Disorders, vol. 24, no. 9, pp. 1339–1343, 2009.
- T. Müller and S. Muhlack, “Cysteinyl-glycine reduction as marker for levodopa-induced oxidative stress in Parkinson's disease patients,” Movement Disorders, vol. 26, no. 3, pp. 543–546, 2011.
- T. Muller and S. Muhlack, “Cysteine decrease following acute levodopa intake in patients with Parkinson’s disease,” Neuroscience Letters, vol. 521, pp. 37–39, 2012.
- R. Dringen, J. M. Gutterer, and J. Hirrlinger, “Glutathione metabolism in brain: metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species,” European Journal of Biochemistry, vol. 267, no. 16, pp. 4912–4916, 2000.
- R. Dringen and J. Hirrlinger, “Glutathione pathways in the brain,” Biological Chemistry, vol. 384, no. 4, pp. 505–516, 2003.
- H. L. Martin and P. Teismann, “Glutathione—a review on its role and significance in Parkinson's disease,” FASEB Journal, vol. 23, no. 10, pp. 3263–3272, 2009.
- J. B. Schulz, J. Lindenau, J. Seyfried, and J. Dichgans, “Glutathione, oxidative stress and neurodegeneration,” European Journal of Biochemistry, vol. 267, no. 16, pp. 4904–4911, 2000.
- E. H. J. M. Kemna, H. Tjalsma, H. L. Willems, and D. W. Swinkels, “Hepcidin: from discovery to differential diagnosis,” Haematologica, vol. 93, no. 1, pp. 90–97, 2008.
- E. Nemeth, E. V. Valore, M. Territo, G. Schiller, A. Lichtenstein, and T. Ganz, “Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein,” Blood, vol. 101, no. 7, pp. 2461–2463, 2003.
- T. Ganz, “Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation,” Blood, vol. 102, no. 3, pp. 783–788, 2003.
- C. Amălinei, D. Căruntu I, S. E. Giuşcă, and R. A. Bălan, “Matrix metalloproteinases involvement in pathologic conditions,” Romanian Journal of Morphology and Embryology, vol. 51, no. 2, pp. 215–228, 2010.
- R. D. Bell and B. V. Zlokovic, “Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease,” Acta Neuropathologica, vol. 118, no. 1, pp. 103–113, 2009.
- C. Chao and A. Ghorpade, “Production and roles of glial tissue inhibitor of metalloproteinases-1 in human immunodeficiency virus-1-associated dementia neuroinflammation: a review,” American Journal of Infectious Diseases, vol. 5, no. 4, pp. 314–320, 2009.
- P. Michaluk and L. Kaczmarek, “Matrix metalloproteinase-9 in glutamate-dependent adult brain function and dysfunction,” Cell Death and Differentiation, vol. 14, no. 7, pp. 1255–1258, 2007.
- Y. Hao, J. Ren, J. Liu, et al., “The protective role of zinc against acute toxicity of depleted uranium in rats,” Basic & Clinical Pharmacology & Toxicology, vol. 111, no. 6, pp. 402–410, 2012.
- A. K. West, J. Hidalgo, D. Eddins, E. D. Levin, and M. Aschner, “Metallothionein in the central nervous system: roles in protection, regeneration and cognition,” Neurotoxicology, vol. 29, no. 3, pp. 489–503, 2008.
- P. H. Chan, “Reactive oxygen radicals in signaling and damage in the ischemic brain,” Journal of Cerebral Blood Flow and Metabolism, vol. 21, no. 1, pp. 2–14, 2001.
- A. C. Maritim, R. A. Sanders, and J. B. Watkins, “Diabetes, oxidative stress, and antioxidants: a review,” Journal of Biochemical and Molecular Toxicology, vol. 17, no. 1, pp. 24–38, 2003.
- H.-J. Tsay, P. Wang, S.-L. Wang, and H.-H. Ku, “Age-associated changes of superoxide dismutase and catalase activities in the rat brain,” Journal of Biomedical Science, vol. 7, no. 6, pp. 466–474, 2000.
- Y. Xiong, F. S. Shie, J. Zhang, C. P. Lee, and Y. S. Ho, “Prevention of mitochondrial dysfunction in post-traumatic mouse brain by superoxide dismutase,” Journal of Neurochemistry, vol. 95, no. 3, pp. 732–744, 2005.