Allergological and Toxicological Aspects in a Multiple Chemical Sensitivity Cohort

Table 4

Increased levels of mercury in biological matrices in patients with MCS who have mercury dental amalgams.

	Patients with mercury amalgam fillings	Patients without mercury amalgam fillings	Total patients	𝑃 value	Odds ratio
Number	24	8	32	0.023	11
Yes	22 (91.7%)	4 (50.0%)	26 (81.3%)
No	2 (8.3%)	4 (50.0%)	6 (18.7%)

In a subgroup analysis of 24 patients, 22 patients with dental amalgam (91.7 percent), levels of total mercury in biological matrices (in aggregate; whole blood, urine, scalp hair, and saliva) correlate with the number of mercury dental amalgam tooth fillings, as compared with 4 patients (50 percent) without dental amalgams (odds ratio, 11; 95 percent confidence interval: from 1.5 to 81.6; 𝑃=0.023).