Clinical Study

Allergological and Toxicological Aspects in a Multiple Chemical Sensitivity Cohort

Table 6

New and classical systemic signs and symptoms associated with mercury exposure among MCS patients cohort.

Signs

(i) AngioedemaN
(ii) Cervical and axillary lymph nodes swollenN
(iii) DermographismC
(iv) Enlargement of thyroidC
(v) Eyelid myokymia (eyelid tremors)N
(vi) Gastrointestinal malabsorptionN
(vii) Gingivitis - StomatitisC
(viii) Lichenoid contact stomatitisN
(ix) Low-grade fever (fever of unknown origin—FUO)N
(x) Muscle atrophyN
(xi) Muscle fasciculationsC
(xii) Non-allergic rhinitis/vasomotor rhinitis-like N
(xiii) Peripheral neuropathyC
(xiv) Salmon-colored and/or pink’ rashC
(xv) Sialorrhea (hypersalivation)C
(xvi) SpasmsC
(xvii) Systemic contact dermatitisN
(xviii) Tremors (upper limb, hands, fingers, face, eyelids,
  and lips)
C
(xix) UrticariaN
(xx) White matter hyperintensity (by brain MRI)N
(xxi) Xerostomia (dry mouth)C

Symptoms

(i) Abdominal crampsN
(ii) AnorexiaC
(iii) Atypical facial pain (persistent idiopathic facial pain)N
(iv) Burning mouth syndrome (BMS)N
(v) Burning pain (neuropathic)C
(vi) Chemical odor intoleranceN
(vii) Chest pain (anterior or posterior, on the left side)N
(viii) ConfusionC
(ix) DepressionC
(x) Dysesthesia N
(xi) FatigueC
(xii) Flu-like symptomsN
(xiii) Headache C
(xiv) InsomniaN
(xv) Intestinal movement disordersN
(xvi) Intolerance to odorsN
(xvii) Itching (neuropathic)N
(xviii) Muscle weaknessC
(xix) NauseaC
(xx) Noise sensitivityN
(xxi) ParesthesiaC
(xxii) PhotophobiaN
(xxiii) Recurrent infectionsN
(xxiv) Short-term memory disturbancesC
(xxv) TachycardiaC
(xxvi) Thermal regulation disorders (low cold tolerance)N
(xxvii) Trigeminal neuralgiaN
(xxviii) VertigoC

The table lists signs and symptoms triggered by mercury amalgam exposure and also noting those defined as “new” and “classical” signs and symptoms related to exposure to mercury amalgam in a cohort of patients with MCS. (N) and (C) denote “new” and “classical” signs and symptoms.