Early Growth Response Protein 1 Promotes Restenosis by Upregulating Intercellular Adhesion Molecule-1 in Vein Graft
Figure 1
Egr-1 KO decreases lumen stenosis in vein grafts at 4 weeks after surgery. (a) Vein grafts from Egr-1 KO mice and WT mice were stained with hematoxylin and eosin (×100). (b) Quantitative analysis of lumen of vein grafts stenosis using NIS Elements BR software (NIKON, Japan). Data are expressed as mean ± SEM. * versus WT/ST group; # versus WT group. WT: inferior vena cava (IVC) in wild-type mice; WT/ST: vein graft from WT mice; Egr-1 KO: IVC in Egr-1 knockout mice; Egr-1 KO/ST: vein graft from Egr-1 knockout mice.
