- About this Journal ·
- Abstracting and Indexing ·
- Advance Access ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Oxidative Medicine and Cellular Longevity
Volume 2013 (2013), Article ID 437146, 9 pages
Saccharomyces cerevisiae Linker Histone—Hho1p Maintains Chromatin Loop Organization during Ageing
Laboratory of Yeast Molecular Genetics, “Acad. Roumen Tsanev” Institute of Molecular Biology, Bulgarian Academy of Sciences,
“Acad. G. Bonchev” Street, Building 21, 1113 Sofia, Bulgaria
Received 10 May 2013; Revised 5 July 2013; Accepted 8 July 2013
Academic Editor: Cristina Mazzoni
Copyright © 2013 Katya Uzunova et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- A. Wolffe, Chromatin Structure and Function, Oxford Press, London, UK, 2nd edition, 1995.
- T. Kouzarides and S. Berger, “Chromatin modifications and their mechanism of action,” in Epigenetics, D. Allis, T. Jenuwein, and D. Reinberg, Eds., pp. 191–209, Cold Spring Harbor Lab Press Press, Cold Spring Harbor, NY, USA, 2007.
- J. T. Bell, P. Tsai, T. Yang et al., “Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population,” PLoS Genetics, vol. 8, no. 4, Article ID e1002629, 2012.
- R. Burgess, T. Misteli, and P. Oberdoerffer, “DNA damage, chromatin, and transcription: the trinity of aging,” Current Opinion in Cell Biology, vol. 24, pp. 724–730, 2012.
- S. Han and A. Brunet, “Histone methylation makes its mark on longevity,” Trends in Cell Biology, vol. 22, no. 1, pp. 42–49, 2012.
- G. Trencsenyi, G. Nagy, F. Bako, P. Kertai, and G. Banfalvi, “Incomplete chromatin condensation in enlarged rat myelocytic leukemia cells,” DNA and Cell Biology, vol. 31, no. 4, pp. 470–478, 2012.
- T. J. Maresca and R. Heald, “The long and the short of it: linker histone H1 is required for metaphase chromosome compaction,” Cell Cycle, vol. 5, no. 6, pp. 589–591, 2006.
- K. Hizume, S. H. Yoshimura, and K. Takeyasu, “Linker histone H1 per se can induce three-dimensional folding of chromatin fiber,” Biochemistry, vol. 44, no. 39, pp. 12978–12989, 2005.
- V. A. T. Huynh, P. J. J. Robinson, and D. Rhodes, “A method for the in vitro reconstitution of a defined “30 nm” chromatin fibre containing stoichiometric amounts of the linker histone,” Journal of Molecular Biology, vol. 345, no. 5, pp. 957–968, 2005.
- G. Pegoraro, N. Kubben, U. Wickert, H. Göhler, K. Hoffmann, and T. Misteli, “Ageing-related chromatin defects through loss of the NURD complex,” Nature Cell Biology, vol. 11, no. 10, pp. 1261–1269, 2009.
- L. Váchová, M. Čáp, and Z. Palková, “Yeast colonies: a model for studies of aging, environmental adaptation, and longevity,” Oxidative Medicine and Cellular Longevity, vol. 2012, Article ID 601836, 8 pages, 2012.
- A. Grzelak, E. Macierzyńska, and G. Bartosz, “Accumulation of oxidative damage during replicative aging of the yeast Saccharomyces cerevisiae,” Experimental Gerontology, vol. 41, no. 9, pp. 813–818, 2006.
- V. Palermo, C. Falcone, and C. Mazzoni, “Apoptosis and aging in mitochondrial morphology mutants of S. cerevisiae,” Folia Microbiologica, vol. 52, no. 5, pp. 479–483, 2007.
- C. Mazzoni, E. Mangiapelo, V. Palermo, and C. Falcone, “Hypothesis: is yeast a clock model to study the onset of humans aging phenotypes?” Frontiers in Oncology, vol. 2, article 203, 2012.
- M. Ždralević, N. Guaragnella, L. Antonacci, E. Marra, and S. Giannattasio, “Yeast as a tool to study signaling pathways in mitochondrial stress response and cytoprotection,” The Scientific World Journal, vol. 2012, Article ID 912147, 10 pages, 2012.
- S. Johnson, P. Rabinovitch, and M. Kaeberlein, “mTOR is a key modulator of ageing and age-related disease,” Nature, vol. 493, no. 338, pp. 338–345, 2013.
- G. Miloshev and M. Georgieva, “The linker histone and chromatin of yeast Saccharomyces cerevisiae,” in Histones Class, Structure and Function, C. H. Shen, Ed., pp. 59–75, Nova, New York, NY, USA, 2012.
- M. Georgieva, A. Roguev, K. Balashev, J. Zlatanova, and G. Miloshev, “Hho1p, the linker histone of Saccharomyces cerevisiae, is important for the proper chromatin organization in vivo,” Biochimica et Biophysica Acta, vol. 1819, no. 5, pp. 366–374, 2012.
- A. Wach, A. Brachat, C. Rebischung et al., “5 PCR-based gene targeting in Saccharomyces cerevisiae,” Methods in Microbiology, vol. 26, pp. 67–83, 1998.
- P. Fabrizio and V. D. Longo, “The chronological life span of Saccharomyces cerevisiae,” Aging Cell, vol. 2, no. 2, pp. 73–81, 2003.
- M. Georgieva, M. Harata, and G. Miloshev, “The nuclear actin-related protein Act3p/Arp4 influences yeast cell shape and bulk chromatin organization,” Journal of Cellular Biochemistry, vol. 104, no. 1, pp. 59–67, 2008.
- D. L. Smith Jr., J. M. McClure, M. Matecic, and J. S. Smith, “Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins,” Aging Cell, vol. 6, no. 5, pp. 649–662, 2007.
- J. A. Downs, E. Kosmidou, A. Morgan, and S. P. Jackson, “Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone,” Molecular Cell, vol. 11, no. 6, pp. 1685–1692, 2003.
- G. Schäfer, C. R. E. McEvoy, and H. Patterton, “The Saccharomyces cerevisiae linker histone Hho1p is essential for chromatin compaction in stationary phase and is displaced by transcription,” Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 39, pp. 14838–14843, 2008.
- M. Breitenbach, M. Jazwinski, and P. Laun, Aging Research in Yeast, vol. 57 of Subcellular Biochemistry, Springer, Berlin, Germany, 2012.
- A. P. Gasch, P. T. Spellman, C. M. Kao et al., “Genomic expression programs in the response of yeast cells to environmental changes,” Molecular Biology of the Cell, vol. 11, no. 12, pp. 4241–4257, 2000.
- P. A. Padilla, E. K. Fuge, M. E. Crawford, A. Errett, and M. Werner-Washburne, “The highly conserved, coregulated SNO and SNZ gene families in Saccharomyces cerevisiae respond to nutrient limitation,” Journal of Bacteriology, vol. 180, pp. 5718–5726, 1998.
- K. Hellauer, E. Sirard, and B. Turcotte, “Decreased expression of specific genes in yeast cells lacking histone H1,” The Journal of Biological Chemistry, vol. 276, no. 17, pp. 13587–13592, 2001.
- P. L. Olive, J. P. Banat, and R. E. Durand, “Heterogeneity in radiation induced DNA damage and repair in tumor and normal cells using the “Comet” assay,” Radiation Research, vol. 122, pp. 86–89, 1990.
- A. Hartmann, E. Agurell, C. Beevers et al., “Recommendations for conducting the in vivo alkaline Comet assay,” Mutagenesis, vol. 18, no. 1, pp. 45–51, 2003.
- J. M. Bryant, J. Govin, L. Zhang, G. Donahue, B. F. Pugh, and S. L. Berger, “The linker histone plays a dual role during gametogenesis in Saccharomyces cerevisiae,” Molecular and Cellular Biology, vol. 32, no. 14, pp. 2771–2783, 2012.
- M. Werner-Washburne, E. L. Braun, M. E. Crawford, and V. M. Peck, “Stationary phase in Saccharomyces cerevisiae,” Molecular Microbiology, vol. 19, no. 6, pp. 1159–1166, 1996.
- R. Zhang and P. D. Adams, “Heterochromatin and its relationship to cell senescence and cancer therapy,” Cell Cycle, vol. 6, no. 7, pp. 784–789, 2007.
- X. Ye, B. Zerlanko, R. Zhang et al., “Definition of pRB- and p53-dependent and -independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci,” Molecular and Cellular Biology, vol. 27, no. 7, pp. 2452–2465, 2007.
- R. Funayama, M. Saito, H. Tanobe, and F. Ishikawa, “Loss of linker histone H1 in cellular senescence,” Journal of Cell Biology, vol. 175, no. 6, pp. 869–880, 2006.