Sweet Chestnut (Castanea sativa Mill.) Bark Extract: Cardiovascular Activity and Myocyte Protection against Oxidative Damage

Figure 4

Effect of CSM bark extract treatment on cell viability in cardiomyocytes exposed to H₂O₂. Cardiomyocytes were treated with CSM bark extract (1–100 μg/mL) for 24 h before the addition of 100 μM H₂O₂, and cellular damage was assessed by the MTT assay and reported as percent cell viability in comparison to control cells. Each bar represents the mean ± S.D. of four independent experiments. *𝑃<0.05 with respect to H₂O₂-treated cells and °𝑃<0.05 with respect to control cells.