- About this Journal ·
- Abstracting and Indexing ·
- Advance Access ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Oxidative Medicine and Cellular Longevity
Volume 2013 (2013), Article ID 574029, 12 pages
Resveratrol Prevents Dendritic Cell Maturation in Response to Advanced Glycation End Products
1Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, 299 Viale Regina Elena, 00161 Rome, Italy
2Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy
3Department of Pharmacology, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey
4Department of Physiology and Pharmacology “Vittorio Erspamer”, La Sapienza University of Rome, 00185 Rome, Italy
Received 1 March 2013; Revised 6 June 2013; Accepted 7 June 2013
Academic Editor: Mahesh Thirunavukkarasu
Copyright © 2013 Brigitta Buttari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- S. R. Thorpe and J. W. Baynes, “Maillard reaction products in tissue proteins: new products and new perspectives,” Amino Acids, vol. 25, no. 3-4, pp. 275–281, 2003.
- R. Ramasamy, F. Y. Shi, and A. M. Schmidt, “RAGE: therapeutic target and biomarker of the inflammatory response—the evidence mounts,” Journal of Leukocyte Biology, vol. 86, no. 3, pp. 505–512, 2009.
- N. Shanmugam, Y. S. Kim, L. Lanting, and R. Natarajan, “Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products,” The Journal of Biological Chemistry, vol. 278, no. 37, pp. 34834–34844, 2003.
- A. Bierhaus, M. A. Hofmann, R. Ziegler, and P. P. Nawroth, “AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept,” Cardiovascular Research, vol. 37, no. 3, pp. 586–600, 1998.
- G. Basta, A. M. Schmidt, and R. de Caterina, “Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes,” Cardiovascular Research, vol. 63, no. 4, pp. 582–592, 2004.
- A. J. Smit and H. L. Lutgers, “The clinical relevance of advanced glycation endproducts (AGE) and recent developments in pharmaceutics to reduce AGE accumulation,” Current Medicinal Chemistry, vol. 11, no. 20, pp. 2767–2784, 2004.
- T. H. Fleming, P. M. Humpert, P. P. Nawroth, and A. Bierhaus, “Reactive metabolites and AGE/RAGE-mediated cellular dysfunction affect the aging process—a mini-review,” Gerontology, vol. 57, no. 5, pp. 435–443, 2011.
- Z. Hegab, S. Gibbons, L. Neyses, and M. A. Mamas, “Role of advanced glycation end products in cardiovascular disease,” World Journal of Cardiology, vol. 4, pp. 90–102, 2012.
- M. A. Baraibar, L. Liu, E. K. Ahmed, and B. Friguet, “Protein oxidative damage at the crossroads of cellular senescence, aging, and age-related diseases,” Oxidative Medicine and Cellular Longevity, vol. 2012, Article ID 919832, 8 pages, 2012.
- B. T. Kurien and R. H. Scofield, “Autoimmunity and oxidatively modified autoantigens,” Autoimmunity Reviews, vol. 7, no. 7, pp. 567–573, 2008.
- J. Ge, Q. Jia, C. Liang et al., “Advanced glycosylation end products might promote atherosclerosis through inducing the immune maturation of dendritic cells,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 25, no. 10, pp. 2157–2163, 2005.
- B. Buttari, E. Profumo, A. Capozzi et al., “Advanced glycation end products of human β2 glycoprotein I modulate the maturation and function of DCs,” Blood, vol. 117, no. 23, pp. 6152–6161, 2011.
- Y. M. Li, T. Mitsuhashi, D. Wojciechowicz et al., “Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins,” Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 20, pp. 11047–11052, 1996.
- A. Miyazaki, H. Nakayama, and S. Horiuchi, “Scavenger receptors that recognize advanced glycation end products,” Trends in Cardiovascular Medicine, vol. 12, no. 6, pp. 258–262, 2002.
- J. Brett, A. M. Schmidt, S. D. Yan et al., “Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues,” The American Journal of Pathology, vol. 143, no. 6, pp. 1699–1712, 1993.
- A. Rojas, F. Delgado-Lopez, I. Gonzalez, R. Perez-Castro, J. Romero, and I. Rojas, “The receptor for advanced glycation end-products: a complex signaling scenario for a promiscuous receptor,” Cellular Signalling, vol. 25, pp. 609–614, 2013.
- A. Agrawal, A. Sridharan, S. Prakash, and H. Agrawal, “Dendritic cells and aging: consequences for autoimmunity,” Expert Review of Clinical Immunology, vol. 8, no. 1, pp. 73–80, 2012.
- S. S. Jensen and M. Gad, “Differential induction of inflammatory cytokines by dendritic cells treated with novel TLR-agonist and cytokine based cocktails: targeting dendritic cells in autoimmunity,” Journal of Inflammation, vol. 7, article 37, 2010.
- Y. Zhang, Z. Luo, L. Ma, Q. Xu, Q. Yang, and L. Si, “Resveratrol prevents the impairment of advanced glycosylation end products (AGE) on macrophage lipid homeostasis by suppressing the receptor for AGE via peroxisome proliferator-activated receptor γ activation,” International Journal of Molecular Medicine, vol. 25, no. 5, pp. 729–734, 2010.
- U. Švajger, N. Obermajer, and M. Jeras, “Dendritic cells treated with resveratrol during differentiation from monocytes gain substantial tolerogenic properties upon activation,” Immunology, vol. 129, no. 4, pp. 525–535, 2010.
- F. Facchiano, A. Lentini, V. Fogliano et al., “Sugar-induced modification of fibroblast growth factor 2 reduces its angiogenic activity in vivo,” The American Journal of Pathology, vol. 161, no. 2, pp. 531–541, 2002.
- F. Facchiano, D. D'Arcangelo, K. Russo et al., “Glycated fibroblast growth factor-2 is quickly produced in vitro upon low-millimolar glucose treatment and detected in vivo in diabetic mice,” Molecular Endocrinology, vol. 20, no. 11, pp. 2806–2818, 2006.
- J. T. Wu, M. C. Tu, and P. Zhung, “Advanced glycation end product (age): characterization of the products from the reaction between d-glucose and serum albumin,” Journal of Clinical Laboratory Analysis, vol. 10, pp. 21–34, 1996.
- A. M. Facchiano, A. Facchiano, and F. Facchiano, “Active Sequences Collection (ASC) database: a new tool to assign functions to protein sequences,” Nucleic Acids Research, vol. 31, no. 1, pp. 379–382, 2003.
- M. S. Aguzzi, F. Facchiano, D. Ribatti et al., “A novel RGDS-analog inhibits angiogenesis in vitro and in vivo,” Biochemical and Biophysical Research Communications, vol. 321, no. 4, pp. 809–814, 2004.
- B. Catalgol, S. Batirel, Y. Taga, and N. K. Ozer, “Resveratrol: French paradox revisited,” Frontiers in Pharmacology, vol. 3, article 141, 2012.
- A. Agrawal, J. Tay, S. Ton, S. Agrawal, and S. Gupta, “Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA,” Journal of Immunology, vol. 182, no. 2, pp. 1138–1145, 2009.
- A. Agrawal, J. Tay, G.-E. Yang, S. Agrawal, and S. Gupta, “Age-associated epigenetic modifications in human DNA increase its immunogenicity,” Aging, vol. 2, no. 2, pp. 93–100, 2010.
- S. Agrawal, A. Agrawal, B. Doughty et al., “Cutting edge: different toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos,” Journal of Immunology, vol. 171, no. 10, pp. 4984–4989, 2003.
- A. Iwasaki and R. Medzhitov, “Regulation of adaptive immunity by the innate immune system,” Science, vol. 327, no. 5963, pp. 291–295, 2010.
- S. Manicassamy and B. Pulendran, “Modulation of adaptive immunity with toll-like receptors,” Seminars in Immunology, vol. 21, no. 4, pp. 185–193, 2009.
- R. M. Steinman, D. Hawiger, and M. C. Nussenzweig, “Tolerogenic dendritic cells,” Annual Review of Immunology, vol. 21, pp. 685–711, 2003.
- Y.-H. Jing, K.-H. Chen, S.-H. Yang, P.-C. Kuo, and J.-K. Chen, “Resveratrol ameliorates vasculopathy in STZ-induced diabetic rats: role of AGE-RAGE signalling,” Diabetes/Metabolism Research and Reviews, vol. 26, no. 3, pp. 212–222, 2010.
- A. M. El-Mowafy and R. E. White, “Resveratrol inhibits MAPK activity and nuclear translocation in coronary artery smooth muscle: reversal of endothelin-1 stimulatory effects,” FEBS Letters, vol. 451, no. 1, pp. 63–67, 1999.
- B. Buttari, E. Profumo, V. Mattei et al., “Oxidized β2-glycoprotein I induces human dendritic cell maturation and promotes a T helper type 1 response,” Blood, vol. 106, no. 12, pp. 3880–3887, 2005.
- E. Profumo, B. Buttari, and R. Riganò, “Oxidized haemoglobin as antigenic target of cell-mediated immune reactions in patients with carotid atherosclerosis,” Autoimmunity Reviews, vol. 8, no. 7, pp. 558–562, 2009.
- E. Profumo, B. Buttari, C. Alessandri et al., “Beta2-glycoprotein I is a target of t cell reactivity in patients with advanced carotid atherosclerotic plaques,” International Journal of Immunopathology and Pharmacology, vol. 23, no. 1, pp. 73–80, 2010.
- B. Buttari, E. Profumo, A. Capozzi, M. Sorice, and R. Riganò, “Oxidized human beta2-glycoprotein i: its impact on innate immune cells,” Current Molecular Medicine, vol. 11, no. 9, pp. 719–725, 2011.
- E. Profumo, B. Buttari, and R. Riganò, “Oxidative stress in cardiovascular inflammation: its involvement in autoimmune responses,” International Journal of Inflammation, vol. 2011, Article ID 295705, 6 pages, 2011.
- S. F. Yan, R. Ramasamy, Y. Naka, and A. M. Schmidt, “Glycation, inflammation, and RAGE: a scaffold for the macrovascular complications of diabetes and beyond,” Circulation Research, vol. 93, no. 12, pp. 1159–1169, 2003.
- H. L. Nienhuis, K. de leeuw, J. Bijzet et al., “Skin autofluorescence is increased in systemic lupus erythematosus but is not reflected by elevated plasma levels of advanced glycation endproducts,” Rheumatology, vol. 47, no. 10, pp. 1554–1558, 2008.
- H. L. A. Nienhuis, J. Westra, A. J. Smit, P. C. Limburg, C. G. M. Kallenberg, and M. Bijl, “AGE and their receptor RAGE in systemic autoimmune diseases: an inflammation propagating factor contributing to accelerated atherosclerosis,” Autoimmunity, vol. 42, no. 4, pp. 302–304, 2009.
- A. L. Y. Tan, J. M. Forbes, and M. E. Cooper, “AGE, RAGE, and ROS in diabetic nephropathy,” Seminars in Nephrology, vol. 27, no. 2, pp. 130–143, 2007.
- M.-P. Wautier, O. Chappey, S. Corda, D. M. Stern, A. M. Schmidt, and J.-L. Wautier, “Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE,” American Journal of Physiology, vol. 280, no. 5, pp. E685–E694, 2001.