Review Article

Pituitary Adenoma Nitroproteomics: Current Status and Perspectives

Figure 6

Nitration site and functional domains of four nitroproteins. (a) Sphingosine-1-phosphate lyase 1. The site 353 K is a pyridoxal phosphate-binding motif. (b) Rho-GTPase-activating protein 5. (c) Zinc finger protein 432. The KRAB domain is a transcriptional suppressor. The ZN-RING is a DNA-binding region. (d) cAMP-dependent protein kinase type I-beta regulatory subunit. Modified from Zhan and Desiderio (2006) [4] with permission from Elsevier Science and reproduced from Zhan and Deiderio (2009) [22] with permission from Springer Science.
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(d)