Mild Systemic Oxidative Stress in the Subclinical Stage of Alzheimer’s Disease

Table 2

Oxidative stress parameters in plasma. INT (cognitively intact patients; 𝑛=42) and AD (patients with probable Alzheimer’s disease; 𝑛=23). Values shown correspond to the means ± SEM. Comparison between average results of the groups was performed using Student’s 𝑡-test for independent samples.

Parameter	INT	AD
Vitamin C (µM)	48±3	52±5
α-Tocopherol (µM)	21±1	17±1^∗
𝛽-Carotene (µM)	0.79±0.9	0.76±1
Lycopene (µM)	0.73±0.09	0.67±0.13
Coenzyme Q10 (µM)	0.15±0.02	0.13±0.03
TBARS (thiobarbituric acid reactive substances) (nmol/mL)	5.82±0.51	5.83±0.62
Oxidized proteins (nmol/mg prot)	0.14±0.01	0.16±0.02

 *𝑃<0.05 was considered significant.