Neuroprotective Function of DJ-1 in Parkinson’s Disease
Figure 2
Cysteine oxidation and activation of DJ-1. DJ-1 contains three cysteine residues at amino acid numbers 46, 54, and 106 (C46, C54, and C106, resp.). C106 is sequentially oxidized with SOH, SO2H, and SO3H, and then C46 and C54 are oxidized or S-nitrosylated.
