The Role of the Keap1/Nrf2 Pathway in the Cellular Response to Methylmercury
Figure 4
MeHg activates Nrf2 in SH-SY5Y cells. (a) Cells were exposed to MeHg (1, 2, 4, or 8 μM) for 6 h, and the total cell lysates (20 μg) were subjected to western blotting with the antibodies indicated. (b) Cells were exposed to MeHg (0.25 or 0.5 μM) for 6, 12, or 24 h, and the total cell lysates (20 μg) were subjected to western blotting with the antibodies indicated. Reprinted from Toyama et al. [42] with the permission of Biochemical Biophysical Research Communications.
