The Role of the Keap1/Nrf2 Pathway in the Cellular Response to Methylmercury

Table 1

Molecular targets of MeHg.

Target protein	In vivo effect	References
Mn-SOD	Reduction of catalytic activity in mouse brain	Shinyashiki et al. [13]
nNOS	Induction of NOS in rat brain	Shinyashiki et al. [15]
Arginase I	Reduction of activity in rat liver; Decreased Mn levels in tissues	Kanda et al. [18]
SDH	Not defined	Kanda et al. [19]