Ulinastatin Suppresses Burn-Induced Lipid Peroxidation and Reduces Fluid Requirements in a Swine Model
Table 2
Effect of ulinastatin on tissue antioxidant enzyme activities.
Variables
Group
Organs
Heart
Lung
Liver
Muscle
Ileum
Cu-Zn SOD#
ILR
3.4 ± 0.5
1.3 ± 0.2
16.3 ± 2.2
1.0 ± 0.2
3.2 ± 0.5
ILR/ULI
3.5 ± 0.6
1.2 ± 0.2
17.3 ± 2.5
0.9 ± 0.1
3.1 ± 0.4
DLR
3.8 ± 0.2
1.2 ± 0.3
17.6 ± 1.4
1.1 ± 0.2
2.9 ± 0.4
DLR/ULI
3.2 ± 0.6
1.0 ± 0.3
16.8 ± 1.9
1.0 ± 0.1
3.0 ± 0.3
MnSOD+
ILR
7.9 ± 1.3
1.7 ± 0.3
6.6 ± 0.8
1.2 ± 0.1
2.2 ± 0.3
ILR/ULI
8.6 ± 1.5
1.5 ± 0.3
6.8 ± 0.8
1.3 ± 0.3
2.1 ± 0.4
DLR
8.4 ± 1.4
1.5 ± 0.2
6.3 ± 0.9
1.4 ± 0.2
2.2 ± 0.3
DLR/ULI
8.3 ± 1.4
1.6 ± 0.4
6.6 ± 0.7
1.3 ± 0.2
2.4 ± 0.3
Catalase
ILR
42.6 ± 5.6
54.3 ± 6.2
485.2 ± 73.1
8.6 ± 1.1
34.0 ± 6.5
ILR/ULI
46.6 ± 8.3
57.0 ± 7.5
428.8 ± 63.7
7.6 ± 1.4
37.4 ± 8.5
DLR
47.3 ± 6.1
56.3 ± 4.6
523.5 ± 59.5
8.6 ± 1.3
32.5 ± 4.4
DLR/ULI
42.6 ± 5.7
54.3 ± 6.2
489.3 ± 76.5
8.6 ± 1.4
32.6 ± 5.3
Data were expressed as mean ± SD of units per milligram of protein. –10 in each group.
#Copper zinc superoxide dismutase.
+Manganese superoxide dismutase.
