Review Article

Phytoagents for Cancer Management: Regulation of Nucleic Acid Oxidation, ROS, and Related Mechanisms

Figure 1

Genetic heterogeneity following nucleic acid oxidation is a major driving force of cancer progression. ROS causes the oxidation of DNA bases. Subsequent base excision repair (BER) introduces genetic errors during the repair process, and the accumulation of these errors drives cancer progression.
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