Cerebroprotective Effect of Moringa oleifera against Focal Ischemic Stroke Induced by Middle Cerebral Artery Occlusion
Table 2
Effect of Moringa oleifera leaves extract on foot withdrawal time in animal model of focal ischemic stroke ().
Treatment
Foot withdrawal time (seconds)
Days after MCAO
7 days
14 days
21 days
Vehicle + Sham operation
1.84 ± 0.17
1.70 ± 0.15
1.88 ± 0.16
Vehicle + MCAO
4.30 ± 0.63aaa
3.79 ± 0.55aaa
3.76 ± 0.20aaa
Piracetam + MCAO
3.42 ± 0.35
3.12 ± 0.30
2.73 ± 0.07***
Vitamin C + MCAO
2.48 ± 0.29**
2.98 ± 0.27
2.71 ± 0.08***
M. oleifera 100 mg/kg + MCAO
3.40 ± 0.27
2.60 ± 0.49*
3.08 ± 0.20**
M. oleifera 200 mg/kg + MCAO
3.17 ± 0.24*
2.12 ± 0.33**
2.27 ± 0.11***
M. oleifera 400 mg/kg + MCAO
3.43 ± 0.38
2.42 ± 0.28**
2.72 ± 0.24***
Data were expressed as mean ± SEM. P value < .001, compared to vehicle plus sham operation. P value < .05, .01, and .001, respectively, compared to vehicle plus MCAO.