Achieving the Balance between ROS and Antioxidants: When to Use the Synthetic Antioxidants

Figure 4

The optimal situation: the physiological balance between the ROS production and antioxidative defenses prevents the accumulation of damage by ROS and enables enough ROS for signaling. Enzymatic and nonenzymatic antioxidants can neutralize ROS and RNS and decrease oxidative stress and restore the balance.