Oxidative Stress and Antioxidant Activity in Hypothermia and Rewarming: Can RONS Modulate the Beneficial Effects of Therapeutic Hypothermia?
Table 2
Selected data showing the protection induced by the experimental hypothermia. This table summarizes information about the impact of the experimental hypothermia on oxidant/antioxidant parameters. Despite the different levels of hypothermia, animal species, tissues, or injury models, the overall effects are as follows. First hypothermia by itself induces an increase in oxidative stress markers and in the reduced glutathione. Second, if hypothermia is applied during another injury there is a decrease in oxidative stress and the maintenance or improvement of antioxidants.
