Review Article

Link between Cancer and Alzheimer Disease via Oxidative Stress Induced by Nitric Oxide-Dependent Mitochondrial DNA Overproliferation and Deletion

Figure 2

The schematic drawing pattern of the GRK2 overexpression that most likely appeared to be as a compensatory to the hypoxia and hypoperfusion induced oxidative stress that initiates the development and maturation of AD. Modified and reprinted with permission of CNS Neurol Disord Drug Targets [92].
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