| Marker | Role | Association with Alzheimer disease |
| Cyclin A | S to G2/M | [95, 96] | Cyclin B | G2/M | [97–99] | Cyclin C | No known role | | Cyclin D (D1, D3) | G0/G1/lateG1/S | [98–101] | Cyclin E | G1 to G1/S | [97, 102] | p34cdc2/cdk 1 | Late G2/M | [95, 96, 103, 104] | Cdk4/Cdk6 | G1/G1/S | [105–108] | Cdk5/p25/p35 | G2 D1, D3 G1 Cyclins | [109–114] | Nclk cdc2-like kinase | Cyclin A kinase | [109, 115, 116] | Cdk7/MPM2 | CDK activated kinase | [101, 117] | Cdc42/rac | GTPase/cell division | | p21ras | G protein/MAPK | [118, 119] | MRG 15 | M phase regulator | [120] | Ki-67 | LateG1,S,G2,M | [97, 120] | p105/pRb | G2/M TF | [105, 120] | PCNA | non cell-cycle specific | [99] | p107/pRb | Cdk2/4/6, check pt | [77, 105] (negative association) | c-myc | S to G2 checkpoint | [77] (negative association) | p53/MDM2 | Repressor complex | [118, 120, 121] | ATM | Check-point | [77] | Raf/Raf-1 | Check point kinase | [117] | p16INK4a p18p15p19 | CyclinD/cdk4/6 inhibitors of M phase | [101, 122] | p27/Kip1 | Cyclin D and E/cdk7 inhibitor | [77] (negative association), [101] | WAF-1/p21/Cip1 | Multi-Cyclin/cdk-inhibitor (G1 and S) | [118] | Plk1/cdc5 Polo-like kinase | G2/M M check point | [123] | PP2A or PP2B | Phosphatase (Cdk5, cdc2) | [124–126] | PP-1 | | [112, 124] | Cdc25 Cdc25A | Phosphatase G2/M | [127, 128] | PKC/Wnt path | Translation control | [129–132] | PKA | Kinase | [133, 134] | PKN | Kinase | [135] | PI3K | Kinase | [136, 137] | AKT/PKB/RAC | Kinase | [135, 138, 139] | TGFBeta/TAK | Kinase | [140, 141] | p44/p42 MAPK (ERK1/2) | MAP kinase | [95, 142–146] | CamK | Kinase Ca/calmodulin regulated | [147] | p38 MAPK | Kinase | [146, 148, 149] | JNK/(SAPK-2/3)-alpha gamma | Kinase (stress activated) | [146, 150] | MEK | MAPK kinase | [122, 151] | GSK-3 and beta Catenin | Proline-dependent protein kinase (PDPK) | [111, 112, 131, 138, 152–157] | P120/E-cadherin | Adhesion complex | [158] | c-fos | TF/regulator | [159] | 14-3-3/14-3-3zeta | Adaptor protein | [160, 161] | c-jun/p38, AP-1 | TF component | [159, 162, 163] | Fyn | Transcription factor | [164, 165] | p53 | TF/DNA damage | [97, 166] | Rho | G-protein | [135] | Rap Rab | G-protein | [117] | Sos-1 | Guanine nucleotide exchange factor | [167] | Grb-2 | Adaptor | [167] |
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