Effect of Centella asiatica on Oxidative Stress and Lipid Metabolism in Hyperlipidemic Animal Models

Table 2

Effect of CAF3 on body weight, liver weight, and liver index in hyperlipidemic golden hamsters.

Groups	Dose (mg/kg d^−1)	Initial body weight (g)	Final body weight (g)	Liver weight (g)	Liver index (g/100 g)
NCD	—	87.00±3.83	96.75±8.97	3.27±0.41	3.33±0.13
HFD	—	87.14±4.74	124.50±4.635^#	7.12±0.32^###	5.73±0.22^###
HFD + XZK	250	87.13±2.70	101.50±4.48^∗	5.76±0.32^∗	5.38±0.10
HFD + C100	100	86.25±2.34	104.00±4.04^∗	5.35±0.27^∗∗	5.06±0.21
HFD + C250	250	85.20±2.19	85.00±5.58^∗∗∗	4.24±0.32^∗∗∗	4.47±0.18^∗∗∗
HFD + C500	500	84.60±2.90	93.75±8.12^∗	5.25±0.53^∗∗	5.59±0.24

Values are expressed as means ± SEM from 8 animals each group; NCD: normal chow diet group; HFD: high-fat diet group; HFD + XZK: high-fat diet + Xuezhikang group; HFD + C100, HFD + C250, HFD + C500: high-fat diet + CAF3 (100, 250, 500 mg/kg) group, respectively.
^#𝑃<0.05, ^###𝑃<0.001 compared to NCD.
^∗𝑃<0.05, ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001 compared to HFD.