Research Article

Withania coagulans Fruit Extract Reduces Oxidative Stress and Inflammation in Kidneys of Streptozotocin-Induced Diabetic Rats

Table 1

Effect of Withania coagulans on weight changes of body and kidney to body weight ratio. Twenty-one-day treatment with Withania coagulans extract caused a significant improvement in the body weight and kidney to body weight ratio compared to diabetic controls.

GroupsBody weight (gms)Kidney weight: body weight
Before treatmentDuring treatment

Nondiabetic controls368.166 ± 17.20419.33 ± 22***0.0029 ± 0.00012
Diabetic controls266.4 ± 5.61259.2 ± 5.39***0.00469 ± 0.00017***
W. coagulans treated269.57 ± 7.09

Results are means ± SEM; rats; **, *** from nondiabetic controls; # 0.05 from diabetic controls.