Ghrelin Therapy Improves Survival after Whole-Body Ionizing Irradiation or Combined with Burn or Wound: Amelioration of Leukocytopenia, Thrombocytopenia, Splenomegaly, and Bone Marrow Injury

Figure 1

Ghrelin improved survival after whole-body ionizing irradiation combined with skin burn. -11 per group; experiment was repeated once. For panel (a): versus RI. For panel (b): versus RI and RI + Veh. For panel (c): versus R-B CI and R-B CI + Veh. For panel (d): representing 73% versus 36% survival in ghrelin-treated and vehicle-treated R-B CI mice, respectively. versus RI + Veh; versus RI + Ghrelin. Veh: vehicle; RI: 9.5 Gy; R-B CI: 9.5 Gy and skin burn.

(a) Control mice

(b) RI mice

(c) R-B CI mice

(d) Vehicle versus ghrelin