Research Article
Melatonin Therapy Prevents Programmed Hypertension and Nitric Oxide Deficiency in Offspring Exposed to Maternal Caloric Restriction
Table 4
Genes that changed by RPKM > 0.3 in the kidney of melatonin treated offspring versus control at 1 week of age.
| Gene_ID | Gene symbol | Fold changes | Log2 | value |
| Upregulated: 439 genes | ENSRNOG00000038989 | D3ZSD6_RAT | 28.686 | 4.842 | 0.0083 | ENSRNOG00000006367 | Slc5a8 | 19.264 | 4.268 | 0.0001 | ENSRNOG00000003038 | Sft2d2 | 17.101 | 4.096 | 0.0020 | ENSRNOG00000007720 | F1LX97_RAT | 13.841 | 3.791 | 0.0027 | ENSRNOG00000019014 | Ndst1 | 12.657 | 3.662 | 0.0003 | ENSRNOG00000017434 | Mgat3 | 12.364 | 3.628 | 0.0005 | ENSRNOG00000001656 | Kcnj15 | 11.724 | 3.551 | 0.0028 | ENSRNOG00000021292 | — | 11.449 | 3.517 | 0.0015 | ENSRNOG00000017078 | Sepn1 | 11.107 | 3.473 | 0.0011 | ENSRNOG00000030121 | Enpep | 10.970 | 3.456 | 0.0029 | ENSRNOG00000005854 | Angpt1 | 10.920 | 3.449 | 0.0165 | ENSRNOG00000009944 | LOC314407 | 10.858 | 3.441 | 0.0017 | ENSRNOG00000013279 | Scd | 10.775 | 3.430 | 0.0012 | ENSRNOG00000001724 | LOC678704 | 10.690 | 3.418 | 0.0011 | ENSRNOG00000002463 | LOC682752 | 10.633 | 3.411 | 0.0033 | ENSRNOG00000011630 | Ak3l1 | 10.304 | 3.365 | 0.0441 | ENSRNOG00000005447 | RGD1311564 | 10.117 | 3.339 | 0.0026 | ENSRNOG00000009019 | Slc6a6 | 10.090 | 3.335 | 0.0016 | ENSRNOG00000002969 | Itpkb | 9.892 | 3.306 | 0.0020 | ENSRNOG00000037307 | Spata22 | 9.876 | 3.304 | 0.0036 | ENSRNOG00000039717 | Ipo11 | 9.584 | 3.261 | 0.0069 | ENSRNOG00000025372 | Glce | 9.536 | 3.253 | 0.0023 | ENSRNOG00000037884 | Oxgr1 | 9.510 | 3.249 | 0.0169 | ENSRNOG00000021203 | Atl3 | 9.487 | 3.246 | 0.0056 | ENSRNOG00000006787 | Dhcr24 | 9.328 | 3.222 | 0.0023 | ENSRNOG00000015038 | Adam10 | 9.279 | 3.214 | 0.0005 | ENSRNOG00000002519 | Magt1 | 9.253 | 3.210 | 0.0010 | ENSRNOG00000038933 | D3ZF12_RAT | 9.225 | 3.206 | 0.0023 | ENSRNOG00000024757 | RGD1310444 | 9.119 | 3.189 | 0.0066 | ENSRNOG00000030285 | Epha3 | 9.064 | 3.180 | 0.0032 | ENSRNOG00000018338 | Vwa1 | 9.017 | 3.173 | 0.0355 | ENSRNOG00000022802 | Tmem184b | 8.982 | 3.167 | 0.0070 | ENSRNOG00000013265 | Tgfbr2 | 8.947 | 3.161 | 0.0014 | ENSRNOG00000026941 | Tril | 8.934 | 3.159 | 0.0024 | ENSRNOG00000020532 | Kcnq1 | 8.904 | 3.154 | 0.0441 | ENSRNOG00000018503 | LOC293190 | 8.862 | 3.148 | 0.0172 | ENSRNOG00000002198 | LOC685352 | 8.711 | 3.123 | 0.0037 | ENSRNOG00000017172 | Fam125b | 8.706 | 3.122 | 0.0291 | ENSRNOG00000018554 | — | 8.663 | 3.115 | 0.0067 | ENSRNOG00000013963 | IL6RB_RAT | 8.571 | 3.099 | 0.0023 | ENSRNOG00000042565 | — | 8.547 | 3.095 | 0.0114 | ENSRNOG00000032834 | Hspa13 | 8.544 | 3.095 | 0.0011 | ENSRNOG00000002355 | Slc47a1 | 8.474 | 3.083 | 0.0025 | ENSRNOG00000011927 | SDC3_RAT | 8.460 | 3.081 | 0.0065 | ENSRNOG00000042540 | Mef2a | 8.454 | 3.080 | 0.0368 | ENSRNOG00000029216 | Dgcr2 | 8.331 | 3.059 | 0.0175 | ENSRNOG00000023725 | LOC689756 | 8.215 | 3.038 | 0.0191 | ENSRNOG00000028129 | Fktn | 8.207 | 3.037 | 0.0063 | ENSRNOG00000000547 | Tspyl4 | 8.202 | 3.036 | 0.0103 | ENSRNOG00000011859 | Eif5a2 | 8.192 | 3.034 | 0.0403 | ENSRNOG00000028387 | E9PTK5_RAT | 8.168 | 3.030 | 0.0197 | ENSRNOG00000015986 | Rassf8 | 8.134 | 3.024 | 0.0094 | ENSRNOG00000029409 | Gstm6l | 8.062 | 3.011 | 0.0292 | ENSRNOG00000008895 | Hnf4a | 7.993 | 2.999 | 0.0398 | ENSRNOG00000038149 | Defb9 | 7.948 | 2.991 | 0.0437 | ENSRNOG00000040287 | Cyp1b1 | 7.890 | 2.980 | 0.0439 | ENSRNOG00000010468 | Elovl6 | 7.871 | 2.977 | 0.0394 | ENSRNOG00000014524 | F1M9D3_RAT | 7.828 | 2.969 | 0.0077 | ENSRNOG00000014209 | Utp6 | 7.793 | 2.962 | 0.0050 | ENSRNOG00000013419 | Agphd1 | 7.789 | 2.961 | 0.0031 | ENSRNOG00000020653 | S1pr2 | 7.775 | 2.959 | 0.0313 | ENSRNOG00000018714 | Arl5b | 7.770 | 2.958 | 0.0078 | ENSRNOG00000002408 | Rbm47 | 7.719 | 2.948 | 0.0057 | ENSRNOG00000008971 | Hnf4g | 7.715 | 2.948 | 0.0085 | ENSRNOG00000011271 | Mcc | 7.688 | 2.943 | 0.0120 | ENSRNOG00000002276 | LOC100359714 | 7.641 | 2.934 | 0.0073 | ENSRNOG00000009446 | Rxra | 7.607 | 2.927 | 0.0066 | ENSRNOG00000019400 | Dag1 | 7.591 | 2.924 | 0.0010 | ENSRNOG00000013098 | F1M9J1_RAT | 7.581 | 2.922 | 0.0320 | ENSRNOG00000014511 | Alg10 | 7.551 | 2.917 | 0.0076 | ENSRNOG00000012490 | Amph | 7.533 | 2.913 | 0.0461 | ENSRNOG00000014934 | Fam63b | 7.481 | 2.903 | 0.0193 | ENSRNOG00000039630 | LOC290577 | 7.414 | 2.890 | 0.0045 | ENSRNOG00000032707 | Egf | 7.368 | 2.881 | 0.0017 | ENSRNOG00000015605 | Ptprk | 7.357 | 2.879 | 0.0298 | ENSRNOG00000000168 | Gatm | 7.311 | 2.870 | 0.0017 | ENSRNOG00000027097 | F1M683_RAT | 7.273 | 2.863 | 0.0087 | ENSRNOG00000018109 | Clic4 | 7.251 | 2.858 | 0.0048 | ENSRNOG00000008629 | Secisbp2l | 7.236 | 2.855 | 0.0042 | ENSRNOG00000019799 | Pcdhgc3 | 7.231 | 2.854 | 0.0246 | ENSRNOG00000024089 | Fndc3b | 7.221 | 2.852 | 0.0065 | ENSRNOG00000015852 | D4AD82_RAT | 7.192 | 2.846 | 0.0020 | ENSRNOG00000006967 | Xiap | 7.151 | 2.838 | 0.0136 | ENSRNOG00000031487 | F1LM52_RAT | 7.129 | 2.834 | 0.0477 | ENSRNOG00000014866 | Pign | 7.077 | 2.823 | 0.0190 | ENSRNOG00000033206 | Entpd5 | 7.060 | 2.820 | 0.0070 | ENSRNOG00000037753 | Slc10a2 | 7.002 | 2.808 | 0.0089 | ENSRNOG00000040195 | F1LZT0_RAT | 7.001 | 2.808 | 0.0018 | ENSRNOG00000042817 | D4A5M8_RAT | 6.925 | 2.792 | 0.0104 | ENSRNOG00000005070 | Spopl | 6.920 | 2.791 | 0.0139 | ENSRNOG00000006459 | D4AEA4_RAT | 6.871 | 2.781 | 0.0251 | ENSRNOG00000012784 | Gtf3c4 | 6.850 | 2.776 | 0.0096 | ENSRNOG00000016968 | Gramd4 | 6.838 | 2.774 | 0.0216 | ENSRNOG00000004448 | RGD1307051 | 6.819 | 2.770 | 0.0050 | ENSRNOG00000021809 | Gpx3 | 6.801 | 2.766 | 0.0008 | ENSRNOG00000014183 | Gnaq | 6.801 | 2.766 | 0.0084 | ENSRNOG00000012991 | LOC100363275 | 6.798 | 2.765 | 0.0046 | ENSRNOG00000013443 | Tm9sf3 | 6.791 | 2.764 | 0.0040 | ENSRNOG00000042673 | LOC100359544 | 6.789 | 2.763 | 0.0012 | ENSRNOG00000003873 | Cpd | 6.767 | 2.758 | 0.0028 | ENSRNOG00000007990 | Adipor2 | 6.762 | 2.758 | 0.0026 | ENSRNOG00000007804 | C1galt1 | 6.762 | 2.757 | 0.0109 | ENSRNOG00000043256 | D3ZNR8_RAT | 6.720 | 2.749 | 0.0145 | ENSRNOG00000015124 | Gpam | 6.720 | 2.748 | 0.0109 | ENSRNOG00000004888 | Spred2 | 6.690 | 2.742 | 0.0454 | ENSRNOG00000003960 | Tmem27 | 6.682 | 2.740 | 0.0026 | ENSRNOG00000015750 | Wnt7b | 6.654 | 2.734 | 0.0218 | ENSRNOG00000030763 | Dpp4 | 6.601 | 2.723 | 0.0011 | ENSRNOG00000039504 | Q5M885_RAT | 6.562 | 2.714 | 0.0116 | ENSRNOG00000032768 | D3Z9G8_RAT | 6.497 | 2.700 | 0.0214 | ENSRNOG00000039771 | LOC100361629 | 6.494 | 2.699 | 0.0140 | ENSRNOG00000009274 | Fut11 | 6.475 | 2.695 | 0.0354 | ENSRNOG00000027938 | RGD1562037 | 6.420 | 2.683 | 0.0117 | ENSRNOG00000001335 | Zkscan1 | 6.419 | 2.682 | 0.0077 | ENSRNOG00000004978 | Prkacb | 6.379 | 2.673 | 0.0216 | ENSRNOG00000005446 | Gna11 | 6.363 | 2.670 | 0.0172 | ENSRNOG00000003884 | Acmsd | 6.362 | 2.669 | 0.0262 | ENSRNOG00000028190 | D4ACF8_RAT | 6.354 | 2.668 | 0.0432 | ENSRNOG00000006338 | Lrp6 | 6.351 | 2.667 | 0.0041 | ENSRNOG00000009523 | Rab11fip2 | 6.345 | 2.666 | 0.0470 | ENSRNOG00000003759 | Galc | 6.345 | 2.666 | 0.0140 | ENSRNOG00000010620 | NDC1_RAT | 6.319 | 2.660 | 0.0275 | ENSRNOG00000001821 | Adipoq | 6.306 | 2.657 | 0.0244 | ENSRNOG00000038572 | RGD1562646 | 6.293 | 2.654 | 0.0106 | ENSRNOG00000026120 | Fam8a1 | 6.282 | 2.651 | 0.0129 | ENSRNOG00000025476 | RGD1359349 | 6.243 | 2.642 | 0.0126 | ENSRNOG00000019508 | Wars2 | 6.216 | 2.636 | 0.0317 | ENSRNOG00000008271 | Fam91a1 | 6.216 | 2.636 | 0.0031 | ENSRNOG00000017120 | Abhd2 | 6.208 | 2.634 | 0.0278 | ENSRNOG00000010843 | Nhlrc3 | 6.203 | 2.633 | 0.0255 | ENSRNOG00000030704 | F1LV74_RAT | 6.139 | 2.618 | 0.0369 | ENSRNOG00000002509 | Gnl3l | 6.129 | 2.616 | 0.0124 | ENSRNOG00000010841 | Col8a2 | 6.089 | 2.606 | 0.0457 | ENSRNOG00000002728 | Btc | 6.088 | 2.606 | 0.0348 | ENSRNOG00000027320 | Eif2c1 | 6.082 | 2.605 | 0.0243 | ENSRNOG00000009453 | Mobkl2b | 6.072 | 2.602 | 0.0271 | ENSRNOG00000007797 | Rbpsuh | 6.069 | 2.602 | 0.0133 | ENSRNOG00000017286 | HYES_RAT | 6.064 | 2.600 | 0.0032 | ENSRNOG00000002461 | Nid1 | 6.057 | 2.599 | 0.0014 | ENSRNOG00000006649 | Thrb | 6.048 | 2.596 | 0.0180 | ENSRNOG00000025042 | Pde3a | 6.048 | 2.596 | 0.0189 | ENSRNOG00000015916 | Ttc38 | 6.048 | 2.596 | 0.0384 | ENSRNOG00000013581 | Extl3 | 6.038 | 2.594 | 0.0093 | ENSRNOG00000002332 | MSPD1_RAT | 6.034 | 2.593 | 0.0213 | ENSRNOG00000032757 | D3Z903_RAT | 6.032 | 2.593 | 0.0431 | ENSRNOG00000029651 | Rdh2 | 6.025 | 2.591 | 0.0258 | ENSRNOG00000018588 | Sox4 | 6.019 | 2.590 | 0.0342 | ENSRNOG00000012428 | Maf | 6.005 | 2.586 | 0.0483 | ENSRNOG00000009506 | Mre11a | 6.005 | 2.586 | 0.0332 | ENSRNOG00000028330 | — | 5.987 | 2.582 | 0.0375 | ENSRNOG00000034025 | D4A4T5_RAT | 5.979 | 2.580 | 0.0227 | ENSRNOG00000007079 | Met | 5.979 | 2.580 | 0.0117 | ENSRNOG00000008088 | Btbd3 | 5.979 | 2.580 | 0.0181 | ENSRNOG00000017546 | Mylk3 | 5.945 | 2.572 | 0.0224 | ENSRNOG00000042333 | Dnal1 | 5.895 | 2.559 | 0.0187 | ENSRNOG00000001092 | Kl | 5.873 | 2.554 | 0.0106 | ENSRNOG00000016498 | — | 5.836 | 2.545 | 0.0049 | ENSRNOG00000037765 | Lims1 | 5.833 | 2.544 | 0.0367 | ENSRNOG00000010267 | Klhdc10 | 5.827 | 2.543 | 0.0346 | ENSRNOG00000043277 | D3ZIC7_RAT | 5.809 | 2.538 | 0.0206 | ENSRNOG00000024799 | D3ZNV9_RAT | 5.803 | 2.537 | 0.0032 | ENSRNOG00000004919 | Gns | 5.795 | 2.535 | 0.0282 | ENSRNOG00000015080 | Wdfy1 | 5.766 | 2.528 | 0.0292 | ENSRNOG00000009565 | Pdk4 | 5.764 | 2.527 | 0.0206 | ENSRNOG00000013082 | LCAP_RAT | 5.754 | 2.525 | 0.0322 | ENSRNOG00000026501 | Slc6a19 | 5.742 | 2.522 | 0.0406 | ENSRNOG00000009597 | Cyp4a1 | 5.740 | 2.521 | 0.0123 | ENSRNOG00000011560 | Mtmr9 | 5.738 | 2.521 | 0.0368 | ENSRNOG00000022710 | Prrg4 | 5.736 | 2.520 | 0.0269 | ENSRNOG00000013469 | LOC100362805 | 5.715 | 2.515 | 0.0059 | ENSRNOG00000024640 | RGD1304731 | 5.698 | 2.510 | 0.0080 | ENSRNOG00000018952 | Sema3g | 5.692 | 2.509 | 0.0143 | ENSRNOG00000020011 | Q66HF5_RAT | 5.677 | 2.505 | 0.0381 | ENSRNOG00000012826 | Creb3l2 | 5.665 | 2.502 | 0.0189 | ENSRNOG00000032492 | Usp22 | 5.657 | 2.500 | 0.0107 | ENSRNOG00000021840 | LOC500046 | 5.644 | 2.497 | 0.0118 | ENSRNOG00000034026 | Lclat1 | 5.642 | 2.496 | 0.0223 | ENSRNOG00000009153 | Cidec | 5.642 | 2.496 | 0.0432 | ENSRNOG00000028899 | Zbtb33 | 5.633 | 2.494 | 0.0168 | ENSRNOG00000001766 | Tfrc | 5.613 | 2.489 | 0.0102 | ENSRNOG00000017901 | Acy3 | 5.613 | 2.489 | 0.0044 | ENSRNOG00000012095 | Pkia | 5.596 | 2.484 | 0.0339 | ENSRNOG00000001796 | Dgkg | 5.573 | 2.479 | 0.0471 | ENSRNOG00000004958 | RGD1304605 | 5.563 | 2.476 | 0.0100 | ENSRNOG00000025587 | Plagl1 | 5.550 | 2.472 | 0.0289 | ENSRNOG00000027540 | Fam102b | 5.536 | 2.469 | 0.0410 | ENSRNOG00000001518 | Itga6 | 5.519 | 2.465 | 0.0452 | ENSRNOG00000032723 | Eftud1 | 5.515 | 2.463 | 0.0336 | ENSRNOG00000002053 | F1M3H3_RAT | 5.491 | 2.457 | 0.0081 | ENSRNOG00000003472 | Atp11c-ps1 | 5.473 | 2.452 | 0.0317 | ENSRNOG00000003984 | Apln | 5.448 | 2.446 | 0.0337 | ENSRNOG00000012453 | RGD1564560 | 5.438 | 2.443 | 0.0046 | ENSRNOG00000017846 | Slc44a1 | 5.422 | 2.439 | 0.0293 | ENSRNOG00000016921 | Klhl11 | 5.418 | 2.438 | 0.0275 | ENSRNOG00000026415 | D4A301_RAT | 5.403 | 2.434 | 0.0280 | ENSRNOG00000013798 | Fnbp1l | 5.391 | 2.431 | 0.0098 | ENSRNOG00000003620 | Fmo3 | 5.384 | 2.429 | 0.0050 | ENSRNOG00000018220 | Pde4dip | 5.377 | 2.427 | 0.0462 | ENSRNOG00000000145 | Pik3r3 | 5.352 | 2.420 | 0.0210 | ENSRNOG00000008834 | LOC306096 | 5.351 | 2.420 | 0.0356 | ENSRNOG00000025882 | Nipal1 | 5.345 | 2.418 | 0.0306 | ENSRNOG00000010996 | Mobkl1a | 5.341 | 2.417 | 0.0147 | ENSRNOG00000001582 | Bach1 | 5.339 | 2.417 | 0.0199 | ENSRNOG00000022309 | D3ZRU8_RAT | 5.313 | 2.410 | 0.0048 | ENSRNOG00000015741 | Slc2a13 | 5.298 | 2.406 | 0.0371 | ENSRNOG00000014303 | F1M753_RAT | 5.294 | 2.404 | 0.0391 | ENSRNOG00000036798 | Dusp3 | 5.284 | 2.402 | 0.0199 | ENSRNOG00000012142 | Glyat | 5.283 | 2.401 | 0.0081 | ENSRNOG00000024426 | D3ZXW1_RAT | 5.259 | 2.395 | 0.0477 | ENSRNOG00000006628 | Dusp16 | 5.256 | 2.394 | 0.0271 | ENSRNOG00000026143 | Ckap2l | 5.230 | 2.387 | 0.0271 | ENSRNOG00000018867 | Klhdc7a | 5.223 | 2.385 | 0.0489 | ENSRNOG00000025296 | Lrrc8a | 5.203 | 2.379 | 0.0176 | ENSRNOG00000014508 | Mgll | 5.203 | 2.379 | 0.0137 | ENSRNOG00000000589 | RGD1310495 | 5.199 | 2.378 | 0.0372 | ENSRNOG00000014234 | Hif1an | 5.192 | 2.376 | 0.0394 | ENSRNOG00000008450 | LOC100359539 | 5.178 | 2.372 | 0.0409 | ENSRNOG00000010744 | Nrp1 | 5.177 | 2.372 | 0.0072 | ENSRNOG00000039837 | RGD1563945 | 5.161 | 2.368 | 0.0466 | ENSRNOG00000013177 | Map3k1 | 5.154 | 2.366 | 0.0114 | ENSRNOG00000021719 | F1LX81_RAT | 5.153 | 2.365 | 0.0133 | ENSRNOG00000024629 | Hadha | 5.116 | 2.355 | 0.0126 | ENSRNOG00000014907 | Aldh8a1 | 5.105 | 2.352 | 0.0055 | ENSRNOG00000036673 | Sectm1b | 5.098 | 2.350 | 0.0121 | ENSRNOG00000024794 | Senp5 | 5.096 | 2.349 | 0.0264 | ENSRNOG00000005131 | Lin7c | 5.086 | 2.347 | 0.0289 | ENSRNOG00000002225 | Scarb2 | 5.081 | 2.345 | 0.0116 | ENSRNOG00000020284 | Prkar2a | 5.077 | 2.344 | 0.0215 | ENSRNOG00000014648 | Efnb2 | 5.072 | 2.343 | 0.0303 | ENSRNOG00000002488 | Galnt10 | 5.063 | 2.340 | 0.0437 | ENSRNOG00000017406 | Atrnl1 | 5.056 | 2.338 | 0.0269 | ENSRNOG00000010813 | Tspan14 | 5.048 | 2.336 | 0.0304 | ENSRNOG00000000645 | Reep3 | 5.047 | 2.336 | 0.0262 | ENSRNOG00000018873 | Fam168a | 5.036 | 2.332 | 0.0160 | ENSRNOG00000020253 | RAB1B_RAT | 5.030 | 2.331 | 0.0128 | ENSRNOG00000001235 | Gna12 | 5.012 | 2.325 | 0.0149 | ENSRNOG00000040215 | F1LZL1_RAT | 5.011 | 2.325 | 0.0302 | ENSRNOG00000011619 | Myo9a | 4.988 | 2.319 | 0.0163 | ENSRNOG00000039976 | D3ZHG3_RAT | 4.983 | 2.317 | 0.0137 | ENSRNOG00000016011 | Plekhg1 | 4.971 | 2.314 | 0.0315 | ENSRNOG00000037909 | Ppm1f | 4.964 | 2.312 | 0.0269 | ENSRNOG00000016419 | Pdlim5 | 4.962 | 2.311 | 0.0248 | ENSRNOG00000023280 | Als2 | 4.952 | 2.308 | 0.0166 | ENSRNOG00000005417 | Zhx2 | 4.948 | 2.307 | 0.0430 | ENSRNOG00000017671 | Rasa3 | 4.944 | 2.306 | 0.0403 | ENSRNOG00000016848 | Fzd4 | 4.942 | 2.305 | 0.0255 | ENSRNOG00000003508 | LOC100364400 | 4.942 | 2.305 | 0.0244 | ENSRNOG00000012394 | Bcl2l13 | 4.931 | 2.302 | 0.0466 | ENSRNOG00000018400 | D4AEL2_RAT | 4.931 | 2.302 | 0.0303 | ENSRNOG00000013707 | Spata13 | 4.930 | 2.302 | 0.0445 | ENSRNOG00000002039 | LOC100360066 | 4.930 | 2.301 | 0.0436 | ENSRNOG00000004563 | Sec24a | 4.917 | 2.298 | 0.0191 | ENSRNOG00000020386 | D3ZKH4_RAT | 4.906 | 2.295 | 0.0098 | ENSRNOG00000007419 | Pank3 | 4.900 | 2.293 | 0.0128 | ENSRNOG00000024533 | Aer61 | 4.889 | 2.290 | 0.0382 | ENSRNOG00000027151 | Lrrc58 | 4.886 | 2.289 | 0.0393 | ENSRNOG00000030124 | Ptpn11 | 4.869 | 2.284 | 0.0160 | ENSRNOG00000006131 | Mettl2 | 4.846 | 2.277 | 0.0271 | ENSRNOG00000000407 | Dcbld1 | 4.834 | 2.273 | 0.0412 | ENSRNOG00000008061 | Nuak1 | 4.826 | 2.271 | 0.0360 | ENSRNOG00000037514 | Qser1 | 4.821 | 2.269 | 0.0136 | ENSRNOG00000004959 | Actr2 | 4.807 | 2.265 | 0.0327 | ENSRNOG00000028582 | F1M163_RAT | 4.795 | 2.261 | 0.0045 | ENSRNOG00000043037 | LOC100366023 | 4.788 | 2.259 | 0.0349 | ENSRNOG00000012135 | F1M2H7_RAT | 4.763 | 2.252 | 0.0406 | ENSRNOG00000031069 | D4A9A7_RAT | 4.749 | 2.247 | 0.0462 | ENSRNOG00000023109 | F1LVL2_RAT | 4.736 | 2.244 | 0.0482 | ENSRNOG00000004442 | RGD1311756 | 4.729 | 2.241 | 0.0456 | ENSRNOG00000021318 | Epas1 | 4.723 | 2.240 | 0.0138 | ENSRNOG00000018099 | Itch | 4.702 | 2.233 | 0.0383 | ENSRNOG00000038892 | LOC686123 | 4.691 | 2.230 | 0.0268 | ENSRNOG00000000296 | Aqp6 | 4.685 | 2.228 | 0.0310 | ENSRNOG00000014901 | Uggt1 | 4.684 | 2.228 | 0.0168 | ENSRNOG00000019659 | Aspa | 4.680 | 2.227 | 0.0055 | ENSRNOG00000010450 | D4ADY9_RAT | 4.662 | 2.221 | 0.0220 | ENSRNOG00000011066 | 6-Mar | 4.658 | 2.220 | 0.0264 | ENSRNOG00000013121 | Mier3 | 4.647 | 2.216 | 0.0408 | ENSRNOG00000030894 | Slco1a6 | 4.640 | 2.214 | 0.0068 | ENSRNOG00000004964 | Erbb3 | 4.609 | 2.205 | 0.0351 | ENSRNOG00000014135 | Rab11fip4 | 4.607 | 2.204 | 0.0453 | ENSRNOG00000005052 | Slc39a9 | 4.594 | 2.200 | 0.0454 | ENSRNOG00000005276 | Csnk2a1 | 4.589 | 2.198 | 0.0259 | ENSRNOG00000015007 | RGD1565591 | 4.583 | 2.196 | 0.0462 | ENSRNOG00000002099 | Wdfy3 | 4.579 | 2.195 | 0.0217 | ENSRNOG00000001747 | Pak2 | 4.572 | 2.193 | 0.0178 | ENSRNOG00000018226 | Zcchc14 | 4.565 | 2.190 | 0.0441 | ENSRNOG00000010702 | Ube3c | 4.564 | 2.190 | 0.0154 | ENSRNOG00000010610 | Hpgd | 4.556 | 2.188 | 0.0125 | ENSRNOG00000001756 | D3ZDR3_RAT | 4.551 | 2.186 | 0.0486 | ENSRNOG00000006335 | Klhl9 | 4.550 | 2.186 | 0.0083 | ENSRNOG00000016715 | Kif11 | 4.547 | 2.185 | 0.0159 | ENSRNOG00000021916 | Slc16a12 | 4.541 | 2.183 | 0.0224 | ENSRNOG00000011250 | Inmt | 4.506 | 2.172 | 0.0125 | ENSRNOG00000013140 | Pdzd2 | 4.502 | 2.171 | 0.0305 | ENSRNOG00000012440 | Msra | 4.501 | 2.170 | 0.0308 | ENSRNOG00000019932 | Ip6k1 | 4.500 | 2.170 | 0.0307 | ENSRNOG00000037227 | Yes1 | 4.499 | 2.170 | 0.0412 | ENSRNOG00000012054 | Zmpste24 | 4.498 | 2.169 | 0.0179 | ENSRNOG00000007370 | Rnf144a | 4.493 | 2.168 | 0.0443 | ENSRNOG00000022968 | F1M4Y9_RAT | 4.491 | 2.167 | 0.0400 | ENSRNOG00000011340 | D3ZMJ4_RAT | 4.488 | 2.166 | 0.0143 | ENSRNOG00000021705 | D3ZXN6_RAT | 4.486 | 2.165 | 0.0229 | ENSRNOG00000003865 | Tmigd1 | 4.483 | 2.164 | 0.0072 | ENSRNOG00000012105 | F1MAE3_RAT | 4.478 | 2.163 | 0.0346 | ENSRNOG00000011312 | F1LQ39_RAT | 4.475 | 2.162 | 0.0366 | ENSRNOG00000000127 | F1LT58_RAT | 4.463 | 2.158 | 0.0484 | ENSRNOG00000022929 | MTMRC_RAT | 4.438 | 2.150 | 0.0307 | ENSRNOG00000033372 | Klhl24 | 4.431 | 2.148 | 0.0197 | ENSRNOG00000008332 | Smo | 4.420 | 2.144 | 0.0209 | ENSRNOG00000028616 | Pck1 | 4.418 | 2.143 | 0.0219 | ENSRNOG00000013281 | Mib1 | 4.415 | 2.142 | 0.0306 | ENSRNOG00000011448 | Eri1 | 4.410 | 2.141 | 0.0414 | ENSRNOG00000028422 | Rmnd5a | 4.409 | 2.141 | 0.0212 | ENSRNOG00000014859 | Rnf152 | 4.404 | 2.139 | 0.0298 | ENSRNOG00000001893 | LOC100362453 | 4.397 | 2.137 | 0.0349 | ENSRNOG00000018123 | Ccny | 4.396 | 2.136 | 0.0173 | ENSRNOG00000016337 | Slc22a1 | 4.394 | 2.135 | 0.0356 | ENSRNOG00000003709 | Kmo | 4.389 | 2.134 | 0.0166 | ENSRNOG00000019939 | CCND2_RAT | 4.386 | 2.133 | 0.0383 | ENSRNOG00000029947 | — | 4.377 | 2.130 | 0.0399 | ENSRNOG00000008346 | Itgb6 | 4.372 | 2.128 | 0.0245 | ENSRNOG00000008678 | Antxr1 | 4.357 | 2.123 | 0.0237 | ENSRNOG00000029924 | Klk1l | 4.344 | 2.119 | 0.0267 | ENSRNOG00000043406 | LOC100360800 | 4.341 | 2.118 | 0.0323 | ENSRNOG00000012343 | Pdp2 | 4.324 | 2.112 | 0.0419 | ENSRNOG00000009899 | D3ZWL1_RAT | 4.306 | 2.106 | 0.0427 | ENSRNOG00000003434 | Trove2 | 4.301 | 2.105 | 0.0368 | ENSRNOG00000015519 | Ces1d | 4.294 | 2.102 | 0.0253 | ENSRNOG00000017439 | Cgnl1 | 4.294 | 2.102 | 0.0236 | ENSRNOG00000014700 | Ttc36 | 4.287 | 2.100 | 0.0266 | ENSRNOG00000007944 | Edem1 | 4.281 | 2.098 | 0.0367 | ENSRNOG00000031263 | Haao | 4.246 | 2.086 | 0.0200 | ENSRNOG00000001647 | Ets2 | 4.245 | 2.086 | 0.0357 | ENSRNOG00000008652 | RGD1564964 | 4.226 | 2.079 | 0.0153 | ENSRNOG00000023202 | Usp15 | 4.217 | 2.076 | 0.0230 | ENSRNOG00000016289 | Bmpr1b | 4.212 | 2.075 | 0.0370 | ENSRNOG00000015024 | E9PT54_RAT | 4.208 | 2.073 | 0.0252 | ENSRNOG00000000555 | Eif4ebp2 | 4.199 | 2.070 | 0.0381 | ENSRNOG00000008620 | Smad3 | 4.198 | 2.070 | 0.0440 | ENSRNOG00000008619 | Agtrap | 4.198 | 2.070 | 0.0217 | ENSRNOG00000009711 | Hepacam2 | 4.196 | 2.069 | 0.0409 | ENSRNOG00000015734 | Ube3a | 4.193 | 2.068 | 0.0225 | ENSRNOG00000015634 | SMAD4_RAT | 4.189 | 2.067 | 0.0277 | ENSRNOG00000042519 | RGD1312026 | 4.182 | 2.064 | 0.0380 | ENSRNOG00000007564 | Evc | 4.160 | 2.057 | 0.0289 | ENSRNOG00000008372 | Vamp7 | 4.160 | 2.057 | 0.0433 | ENSRNOG00000024671 | D4AA13_RAT | 4.157 | 2.056 | 0.0120 | ENSRNOG00000004622 | Calcrl | 4.142 | 2.050 | 0.0131 | ENSRNOG00000009660 | Enpp6 | 4.140 | 2.050 | 0.0247 | ENSRNOG00000014750 | D3ZXU7_RAT | 4.138 | 2.049 | 0.0176 | ENSRNOG00000008694 | Miox | 4.134 | 2.048 | 0.0226 | ENSRNOG00000004831 | Arid2 | 4.134 | 2.047 | 0.0317 | ENSRNOG00000043167 | Itga9 | 4.124 | 2.044 | 0.0349 | ENSRNOG00000001770 | Ehhadh | 4.114 | 2.040 | 0.0104 | ENSRNOG00000042160 | Tmem167b | 4.112 | 2.040 | 0.0466 | ENSRNOG00000018668 | Glg1 | 4.095 | 2.034 | 0.0172 | ENSRNOG00000007985 | D4ABH6_RAT | 4.084 | 2.030 | 0.0231 | ENSRNOG00000014623 | F1M3F2_RAT | 4.071 | 2.026 | 0.0332 | ENSRNOG00000002227 | Kit | 4.056 | 2.020 | 0.0429 | ENSRNOG00000016219 | Vnn1 | 4.052 | 2.019 | 0.0115 | ENSRNOG00000008322 | E9PTI4_RAT | 4.035 | 2.013 | 0.0418 | ENSRNOG00000011358 | Hipk3 | 4.034 | 2.012 | 0.0372 | ENSRNOG00000028335 | Fat4 | 4.017 | 2.006 | 0.0190 | ENSRNOG00000025554 | Zfp445 | 4.009 | 2.003 | 0.0365 | ENSRNOG00000003388 | Cenpf | 3.990 | 1.996 | 0.0146 | ENSRNOG00000000614 | Bicc1 | 3.987 | 1.995 | 0.0162 | ENSRNOG00000039091 | D3ZRC4_RAT | 3.975 | 1.991 | 0.0145 | ENSRNOG00000030154 | Cyp4a2 | 3.962 | 1.986 | 0.0422 | ENSRNOG00000033172 | — | 3.952 | 1.983 | 0.0176 | ENSRNOG00000017466 | Kif5b | 3.949 | 1.981 | 0.0128 | ENSRNOG00000042879 | D4A3X0_RAT | 3.943 | 1.979 | 0.0454 | ENSRNOG00000002146 | Pkd2 | 3.942 | 1.979 | 0.0358 | ENSRNOG00000012940 | Vps41 | 3.937 | 1.977 | 0.0280 | ENSRNOG00000017291 | Sord | 3.928 | 1.974 | 0.0133 | ENSRNOG00000001606 | Adamts5 | 3.923 | 1.972 | 0.0420 | ENSRNOG00000016534 | D3ZKX0_RAT | 3.904 | 1.965 | 0.0295 | ENSRNOG00000007202 | Sema3d | 3.898 | 1.963 | 0.0254 | ENSRNOG00000012436 | Adh6 | 3.897 | 1.962 | 0.0137 | ENSRNOG00000016334 | Rod1 | 3.867 | 1.951 | 0.0167 | ENSRNOG00000018011 | RGD1564456 | 3.867 | 1.951 | 0.0417 | ENSRNOG00000039494 | D4A608_RAT | 3.853 | 1.946 | 0.0328 | ENSRNOG00000014976 | Acsm2 | 3.850 | 1.945 | 0.0330 | ENSRNOG00000006636 | Otud6b | 3.817 | 1.932 | 0.0439 | ENSRNOG00000015849 | Sepp1 | 3.812 | 1.930 | 0.0292 | ENSRNOG00000004689 | Ptdss1 | 3.811 | 1.930 | 0.0342 | ENSRNOG00000013808 | Ces2g | 3.803 | 1.927 | 0.0345 | ENSRNOG00000014673 | Eri2 | 3.791 | 1.922 | 0.0429 | ENSRNOG00000009819 | Vezf1 | 3.784 | 1.920 | 0.0450 | ENSRNOG00000016758 | Loxl2 | 3.783 | 1.919 | 0.0310 | ENSRNOG00000010061 | Gmfb | 3.763 | 1.912 | 0.0466 | ENSRNOG00000023021 | Msl2 | 3.746 | 1.906 | 0.0486 | ENSRNOG00000039571 | Glod5 | 3.742 | 1.904 | 0.0370 | ENSRNOG00000017600 | Ptpn9 | 3.739 | 1.903 | 0.0329 | ENSRNOG00000000590 | Naglt1 | 3.718 | 1.895 | 0.0365 | ENSRNOG00000011511 | Stk24 | 3.716 | 1.894 | 0.0398 | ENSRNOG00000018279 | Sfxn1 | 3.712 | 1.892 | 0.0213 | ENSRNOG00000003953 | RB3GP_RAT | 3.709 | 1.891 | 0.0486 | ENSRNOG00000024632 | Atf6 | 3.699 | 1.887 | 0.0421 | ENSRNOG00000016779 | Fam120a | 3.679 | 1.879 | 0.0257 | ENSRNOG00000010379 | Cugbp1 | 3.670 | 1.876 | 0.0295 | ENSRNOG00000010780 | Dlc1 | 3.664 | 1.874 | 0.0495 | ENSRNOG00000003948 | Llgl1 | 3.659 | 1.871 | 0.0486 | ENSRNOG00000016183 | Ipp | 3.647 | 1.867 | 0.0466 | ENSRNOG00000017964 | Slc22a25 | 3.567 | 1.835 | 0.0201 | ENSRNOG00000039745 | Pm20d1 | 3.557 | 1.831 | 0.0300 | ENSRNOG00000010107 | PALLD_RAT | 3.528 | 1.819 | 0.0467 | ENSRNOG00000019444 | D4ADJ6_RAT | 3.515 | 1.814 | 0.0265 | ENSRNOG00000011260 | Cmbl | 3.513 | 1.813 | 0.0221 | ENSRNOG00000013322 | DPOLA_RAT | 3.505 | 1.810 | 0.0498 | ENSRNOG00000039278 | Mcart1 | 3.477 | 1.798 | 0.0345 | ENSRNOG00000021108 | Slc22a12 | 3.449 | 1.786 | 0.0263 | ENSRNOG00000010887 | RGD1309534 | 3.435 | 1.781 | 0.0382 | ENSRNOG00000008331 | RGD1309995 | 3.394 | 1.763 | 0.0425 | ENSRNOG00000007949 | Rgn | 3.355 | 1.746 | 0.0276 | ENSRNOG00000011987 | Cd2ap | 3.343 | 1.741 | 0.0306 | ENSRNOG00000042175 | B6VQA7_RAT | 3.331 | 1.736 | 0.0384 | ENSRNOG00000012190 | Cldn2 | 3.324 | 1.733 | 0.0347 | ENSRNOG00000023972 | F1M6Q3_RAT | 3.323 | 1.733 | 0.0322 | ENSRNOG00000011763 | Serp1 | 3.319 | 1.731 | 0.0316 | ENSRNOG00000004496 | Rock2 | 3.318 | 1.730 | 0.0337 | ENSRNOG00000004677 | Zeb2 | 3.306 | 1.725 | 0.0306 | ENSRNOG00000013409 | Gclm | 3.301 | 1.723 | 0.0338 | ENSRNOG00000004302 | Pah | 3.270 | 1.709 | 0.0368 | ENSRNOG00000010947 | MMP14_RAT | 3.253 | 1.702 | 0.0337 | ENSRNOG00000011058 | Utrn | 3.247 | 1.699 | 0.0378 | ENSRNOG00000018215 | Slc22a6 | 3.246 | 1.698 | 0.0377 | ENSRNOG00000016456 | Il33 | 3.234 | 1.693 | 0.0319 | ENSRNOG00000002541 | Pds5a | 3.164 | 1.662 | 0.0449 | ENSRNOG00000002680 | Lamc1 | 3.139 | 1.650 | 0.0366 | ENSRNOG00000011124 | Eif4g2-ps1 | 3.125 | 1.644 | 0.0380 | ENSRNOG00000004009 | Xpnpep2 | 3.118 | 1.641 | 0.0414 | ENSRNOG00000010768 | Kpna4 | 3.114 | 1.639 | 0.0499 | ENSRNOG00000042249 | F1LTA7_RAT | 3.101 | 1.633 | 0.0422 | ENSRNOG00000014166 | Smoc2 | 3.078 | 1.622 | 0.0413 | ENSRNOG00000002305 | Slc15a2 | 3.061 | 1.614 | 0.0400 | ENSRNOG00000005130 | Ogdh | 3.049 | 1.608 | 0.0465 | ENSRNOG00000018086 | Slc22a8 | 3.048 | 1.608 | 0.0418 | ENSRNOG00000010814 | Bmpr1a | 3.006 | 1.588 | 0.0432 | ENSRNOG00000032885 | CYC_RAT | 2.936 | 1.554 | 0.0478 |
| Down-regulated Genes: 15 | ENSRNOG00000032087 | F1LWC2_RAT | 0.301 | −1.734 | 0.0328 | ENSRNOG00000032609 | — | 0.300 | −1.738 | 0.0394 | ENSRNOG00000033748 | F1LWC2_RAT | 0.299 | −1.741 | 0.0381 | ENSRNOG00000025670 | Shisa3 | 0.295 | −1.759 | 0.0282 | ENSRNOG00000029115 | — | 0.284 | −1.815 | 0.0315 | ENSRNOG00000011821 | S100a4 | 0.228 | −2.134 | 0.0086 | ENSRNOG00000007632 | Zmynd17 | 0.211 | −2.243 | 0.0365 | ENSRNOG00000025408 | D3ZTT0_RAT | 0.189 | −2.403 | 0.0422 | ENSRNOG00000028844 | Slc9a5 | 0.181 | −2.466 | 0.0282 | ENSRNOG00000006889 | Ambp | 0.150 | −2.741 | 0.0177 | ENSRNOG00000028730 | D3ZI71_RAT | 0.148 | −2.757 | 0.0450 | ENSRNOG00000026067 | Wfdc10 | 0.144 | −2.791 | 0.0123 | ENSRNOG00000037374 | D3ZPQ1_RAT | 0.140 | −2.840 | 0.0087 | ENSRNOG00000033517 | LOC100360791 | 0.129 | −2.950 | 0.0009 | ENSRNOG00000042909 | F1LZX4_RAT | 0.107 | −3.229 | 0.0466 | ENSRNOG00000014578 | Fxyd4 | 0.096 | −3.374 | 0.0001 |
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