Review Article

Signaling Mechanisms and Disrupted Cytoskeleton in the Diphenyl Ditelluride Neurotoxicity

Figure 2

Oxidation of thiol groups from targets proteins by diphenyl ditelluride [(PhTe)2] (a) or by cationic forms of tellurium (Te4+ and Te6+) (b). The oxidation of thiol groups can be catalytic, because the reduced form of ditelluride (tellurol) can be easily oxidized back to (PhTe)2 by molecular oxygen.
458601.fig.002a
(a)
458601.fig.002b
(b)