Pegylated G-CSF Inhibits Blood Cell Depletion, Increases Platelets, Blocks Splenomegaly, and Improves Survival after Whole-Body Ionizing Irradiation but Not after Irradiation Combined with Burn
Figure 6
Peg-G-CSF mitigated both increased spleen weights and decreased splenocyte counts after whole-body ionizing irradiation alone and increased splenocyte counts after irradiation combined with skin burn at day 30 after burn, RI, or CI. per group. versus sham and burn; versus RI; versus sham + Vehicle and burn + Vehicle; versus CI + Vehicle. RI: 9.5 Gy; CI: 9.5 Gy and skin burn.