Effect of the Antihypertensive Drug Enalapril on Oxidative Stress Markers and Antioxidant Enzymes in Kidney of Spontaneously Hypertensive Rat

Figure 4

Kidney section HE stains of enalapril treated and untreated SHR and SHR administered L-NAME. (A) SHR at 16 weeks showing no abnormal changes (40x); (B) SHR at 28 weeks showing presence of mild blood vessel changes, medial hypertrophy (100x); (C) SHR+E at 28 weeks showing no abnormal changes (40x); (D) SHR+LN at 28 weeks showing collapsed glomerulus (a), blood vessel hypertrophy (b), and tubular casts (c)(40x); (E) SHR+LN at 28 weeks showing collapsed glomerulus (a), casts (b), and blood vessel hypertrophy (c) (100x); (F) SHR+E+LN at 28 weeks showing no abnormal changes.